Pathophysiological effects of dietary essential fatty acid balance on neural systems.
Pathophysiological effects of dietary essential fatty acid balance on neural systems.
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膳食必需脂肪酸平衡对神经系统的病理生理学影响。
DOI:
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发表时间:
1998
期刊:
影响因子:
--
通讯作者:
Harumi Okuyama
中科院分区:
文献类型:
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作者:
Satoshi Yoshida;Akira Sato;Harumi Okuyama
Dietary fatty acid balance has been revealed to affect neural functions as well as chronic diseases such as cancer, cerebro- and cardiovascular diseases, and allergic hyper-reactivity. In this review, we focused on the pathophysiological effects of n-6 and n-3 fatty acids on brain functions. Long-term n-3 fatty acid deficiency in the presence of n-6 fatty acids has been shown to affect learning behavior, drug sensitivity and retinal functions. Some membrane enzymes and ion channel functions have been shown in experimental animals to be regulated by membrane fatty acid modifications. We also summarized the effects of these fatty acids in diets on human psychotic aspects and brain diseases. Although biochemical mechanisms remain to be elucidated, investigations on the effect of dietary fatty acids on neural networks may provide an important clue to clarify complex brain functions.
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DOI:
10.1016/s0021-9258(18)54882-1
发表时间:
1991-10
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
A. Voss;M. Reinhart;S. Sankarappa;H. Sprecher
通讯作者:
A. Voss;M. Reinhart;S. Sankarappa;H. Sprecher
DOI:
10.1073/pnas.83.11.4021
发表时间:
1986-06-01
影响因子:
11.1
作者:
NEURINGER, M;CONNOR, WE;LUCK, S
通讯作者:
LUCK, S
DOI:
--
发表时间:
1992
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Deeney,JT;Tornheim,K;Korchak,HM;Prentki,M;Corkey,BE
通讯作者:
Corkey,BE
影响因子:
56.9
作者:
AOSAKI, T;GRAYBIEL, AM;KIMURA, M
通讯作者:
KIMURA, M
DOI:
10.1016/0026-0495(94)90157-0
发表时间:
1994
期刊:
Metabolism: clinical and experimental
影响因子:
--
作者:
Young,JB;Walgren,MC
通讯作者:
Walgren,MC