Stress-induced elevation of oxytocin in maltreated children: evolution, neurodevelopment, and social behavior.

Stress-induced elevation of oxytocin in maltreated children: evolution, neurodevelopment, and social behavior.
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受虐待儿童压力引起的催产素升高:进化、神经发育和社会行为。

DOI:
10.1111/cdev.12136
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发表时间:
2014
期刊:
影响因子:
4.6
通讯作者:
Pollak,SethD
Pollak,SethD
中科院分区:
心理学1区
文献类型:
--
作者:
Seltzer,LeslieJ;Ziegler,Toni;Connolly,MichaelJ;Prososki,AshleyR;Pollak,SethD

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虐待儿童往往对社会行为的发展和健康产生负面影响。然而,这些不良后果产生的生物行为机制尚不清楚。为了更好地了解早期生活逆境影响随后社会行为的方式,研究了8.1-11.5岁儿童(n=8.1-11.5)在实验室应激源后神经肽催产素(OT)的变化。与对照组相比,有身体虐待史的女孩在应激源后尿液OT水平较高,唾液皮质醇水平较低。然而,被虐待和控制的男孩在荷尔蒙反应上没有区别。这些数据表明,早期的逆境可能会扰乱女孩在童年中期的压力调节系统的发展。
Child maltreatment often has a negative impact on the development of social behavior and health. The biobehavioral mechanisms through which these adverse outcomes emerge, however, are not clear. To better understand the ways in which early life adversity affects subsequent social behavior, changes in the neuropeptide oxytocin (OT) in children (n= 73) aged 8.1–11.5 years following a laboratory stressor were examined. Girls with histories of physical abuse have higher levels of urinary OT and lower levels of salivary cortisol following the stressor when compared to controls. Abused and control boys, however, do not differ in their hormonal responses. These data suggest that early adversity may disrupt the development of the stress regulation system in girls by middle childhood.
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DOI: 10.1111/j.1467-8624.1993.tb02902.x
发表时间: 1993
期刊: Child development
影响因子: 4.6
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DOI: --
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DOI: 10.1111/j.1749-6632.1995.tb44681.x
发表时间: 1995-01-01
期刊: STRESS
影响因子: 2.3
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