Differential Impact of Behavioral Relevance on Quantity Coding in Primate Frontal and Parietal Neurons

Differential Impact of Behavioral Relevance on Quantity Coding in Primate Frontal and Parietal Neurons
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行为相关性对灵长类额叶和顶叶神经元数量编码的差异影响

DOI:
10.1016/j.cub.2015.03.025
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发表时间:
2015
期刊:
影响因子:
9.2
通讯作者:
Nieder A.
Nieder A.
中科院分区:
生物学1区
文献类型:
--
作者:
Viswanathan P;Nieder A.

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前额叶皮层 (PFC) 和后顶叶皮层是表示幅度的关键大脑区域。主动辨别数量是否会改变神经元表征尚不清楚。在猴子学会主动辨别一组物品的数量之前和之后,我们同时从前额皮质和腹侧顶内区(VIP)的相同记录位点进行记录。在数字训练后,只有 PFC 神经元(而非 VIP 神经元)表现出更高的数字表示能力。 PFC 反应性的增强表现为神经元群数量分化的增强以及单个选择性神经元编码数量的增加。在 VIP 中没有观察到这些效应,其中神经元总是对数量做出反应,而与行为相关性无关。这表明 PFC 在数字任务需求和执行控制过程中的参与程度较高,而 VIP 将数量编码为感知类别,而不管行为相关性如何。
Prefrontal cortex (PFC) and posterior parietal cortex are key brain areas for magnitude representations. Whether active discrimination of numerosity changes neuronal representations is still not known. We simultaneously recorded from the same recording sites in the PFC and ventral intraparietal area (VIP) before and after monkeys learned to actively discriminate the number of items in a set. Only PFC neurons, and not VIP neurons, exhibited heightened representation of number after numerosity training. Increased responsiveness of PFC was evidenced by enhanced differentiation of numerosity by the population of neurons, as well as increased numerosity encoding by individual selective neurons. None of these effects were observed in the VIP, in which neurons responded invariably to numerosity irrespective of behavioral relevance. This suggests elevated PFC participation during numerical task demands and executive control, whereas VIP encodes quantity as a perceptual category regardless of behavioral relevance.
DOI: --
发表时间: 2017
期刊:
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