Increasing contributions of airborne route in SARS-CoV-2 omicron variant transmission compared with the ancestral strain.
Increasing contributions of airborne route in SARS-CoV-2 omicron variant transmission compared with the ancestral strain.
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DOI：
10.1016/j.buildenv.2022.109328
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发表时间：
2022-08-01
影响因子：
7.4
通讯作者：
Lei, Hao
中科院分区：
文献类型：
--
作者：
Ji, Shuyi;Xiao, Shenglan;Wang, Huaibin;Lei, Hao
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant has become the dominant lineage worldwide.实验研究表明，SARS-CoV-2 Omicron 变种在各种环境表面上比 SARS-CoV-2 的祖先毒株更稳定。 However, the influences on the role of the contact route in SARS-CoV-2 transmission are still unknown.在这项研究中，我们建立了一个马尔可夫链模型来模拟 SARS-CoV-2 的 Omicron 和祖先毒株在 1 天内通过多种途径在家庭内传播； that is, airborne, droplet, and contact routes. We assumed that there were two adults and one child in the household, and that one of the adults was infected with SARS-CoV-2.我们假设了两种情况。 (1) Asymptomatic/presymptomatic infection, and (2) symptomatic infection.在无症状/症状前感染期间，接触途径贡献最大（37%–45%），其次是空气传播途径（34%–38%）和飞沫传播途径（21%–28%）。在有症状感染期间，飞沫途径是主要途径（48%–71%），其次是接触途径（25%–42%），空气传播途径的作用可以忽略不计（<10%）。 Compared to the ancestral strain, although the contribution of the contact route increased in Omicron variant transmission, the increase was slight, from 25%–41% to 30%–45%.随着人们越来越关注 Omicron 菌株传播中无症状/症状前感染比例的增加，空气传播途径，而不是污染物途径，应该受到关注。 Our findings suggest the importance of ventilation in the SARS-CoV-2 Omicron variant prevention in building environment.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant has become the dominant lineage worldwide. Experimental studies have shown that SARS-CoV-2 Omicron variant is more stable on various environmental surfaces than the ancestral strains of SARS-CoV-2. However, the influences on the role of the contact route in SARS-CoV-2 transmission are still unknown. In this study, we built a Markov chain model to simulate the transmission of the Omicron and ancestral strains of SARS-CoV-2 within a household over a 1-day period from multiple pathways; that is, airborne, droplet, and contact routes. We assumed that there were two adults and one child in the household, and that one of the adults was infected with SARS-CoV-2. We assumed two scenarios. (1) Asymptomatic/presymptomatic infection, and (2) symptomatic infection. During asymptomatic/presymptomatic infection, the contact route contributing the most (37%–45%), followed by the airborne (34%–38%) and droplet routes (21%–28%). During symptomatic infection, the droplet route was the dominant pathway (48%–71%), followed by the contact route (25%–42%), with the airborne route playing a negligible role (<10%). Compared to the ancestral strain, although the contribution of the contact route increased in Omicron variant transmission, the increase was slight, from 25%–41% to 30%–45%. With the growing concern about the increase in the proportion of asymptomatic/presymptomatic infection in Omicron strain transmissions, the airborne route, rather than the fomite route, should be of focus. Our findings suggest the importance of ventilation in the SARS-CoV-2 Omicron variant prevention in building environment.
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影响因子：
4.9
作者：
Dumont-Leblond N;Veillette M;Bhérer L;Boissoneault K;Mubareka S;Yip L;Dubuis ME;Longtin Y;Jouvet P;McGeer A;Duchaine C
通讯作者：
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影响因子：
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作者：
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通讯作者：
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DOI：
10.3390/v14030533
发表时间：
2022-03-04
期刊：
Viruses
影响因子：
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通讯作者：
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影响因子：
6.4
作者：
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通讯作者：
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影响因子：
11.8
作者：
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通讯作者：
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