A Rapid Prototyping Technique for Microfluidics with High Robustness and Flexibility.
A Rapid Prototyping Technique for Microfluidics with High Robustness and Flexibility.
复制标题
具有高鲁棒性和灵活性的微流控快速原型技术
DOI：
10.3390/mi7110201
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发表时间：
2016-11-08
期刊：
影响因子：
3.4
通讯作者：
Wu Z
中科院分区：
文献类型：
--
作者：
Liu Z;Xu W;Hou Z;Wu Z
在微流体器件原型设计中，通过传统光刻技术进行母版制造既昂贵又耗时，特别是当设计需要反复修改才能达到令人满意的性能时。通过将高性能/成本比的激光器引入到传统的软光刻技术中，本文描述了一种灵活且快速的微流控原型技术。紫外（UV）激光直接在光刻胶上写入，无需光掩模，适合母版制作。通过消除制作母版时传统光掩模中固定图案的限制，这种原型制作技术为设计者/研究人员提供了迭代修改或修改其设计的便利。通过这种方法制造的装置经过颗粒分离测试并表现出良好的性能。该技术为非专业人员以相对较低的成本制造微流体装置提供了灵活、快速的解决方案。
In microfluidic device prototyping, master fabrication by traditional photolithography is expensive and time-consuming, especially when the design requires being repeatedly modified to achieve a satisfactory performance. By introducing a high-performance/cost-ratio laser to the traditional soft lithography, this paper describes a flexible and rapid prototyping technique for microfluidics. An ultraviolet (UV) laser directly writes on the photoresist without a photomask, which is suitable for master fabrication. By eliminating the constraints of fixed patterns in the traditional photomask when the masters are made, this prototyping technique gives designers/researchers the convenience to revise or modify their designs iteratively. A device fabricated by this method is tested for particle separation and demonstrates good properties. This technique provides a flexible and rapid solution to fabricating microfluidic devices for non-professionals at relatively low cost.
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