Enhancement of human cognitive performance using transcranial magnetic stimulation (TMS).
Enhancement of human cognitive performance using transcranial magnetic stimulation (TMS).
复制标题
DOI：
10.1016/j.neuroimage.2013.06.007
复制
发表时间：
2014-01-15
期刊：
影响因子：
5.7
通讯作者：
Lisanby SH
中科院分区：
文献类型：
--
作者：
Luber B;Lisanby SH
在这里，我们回顾了经颅磁刺激（TMS）在调节皮质网络的方式，可能会产生性能增强健康的人类受试者的有用性。到目前为止，超过60项研究报告了在涉及感知，运动和执行处理的各种任务中的速度和准确性的显着改善。这篇文献提出了两种基本的增强机制：直接调制皮层区域或网络，导致更有效的处理，和加减法，这是处理的破坏，竞争或分散任务的性能。TMS认知增强的潜在应用，包括研究皮层功能，神经和精神疾病的康复治疗，以及健康个体的加速技能获取进行了讨论，以及优化TMS诱导的性能增强的幅度和持续时间的方法，例如通过进一步整合脑成像与TMS来改善靶向。一种技术，结合多个会议的TMS与并发TMS/任务的性能，以诱导赫布式学习，似乎是有前途的延长增强效果。虽然TMS在认知增强中的应用仍然可以进一步改进，并且关于所观察到的效果的机制仍然存在问题，但这似乎是一个富有成效的调查领域，可以揭示认知功能及其治疗调制的基本机制。
Here we review the usefulness of transcranial magnetic stimulation (TMS) in modulating cortical networks in ways that might produce performance enhancements in healthy human subjects. To date over sixty studies have reported significant improvements in speed and accuracy in a variety of tasks involving perceptual, motor, and executive processing. Two basic categories of enhancement mechanisms are suggested by this literature: direct modulation of a cortical region or network that leads to more efficient processing, and addition-by-subtraction, which is disruption of processing which competes or distracts from task performance. Potential applications of TMS cognitive enhancement, including research into cortical function, rehabilitation therapy in neurological and psychiatric illness, and accelerated skill acquisition in healthy individuals are discussed, as are methods of optimizing the magnitude and duration of TMS-induced performance enhancement, such as improvement of targeting through further integration of brain imaging with TMS. One technique, combining multiple sessions of TMS with concurrent TMS/task performance to induce Hebbian-like learning, appears to be promising for prolonging enhancement effects. While further refinements in the application of TMS to cognitive enhancement can still be made, and questions remain regarding the mechanisms underlying the observed effects, this appears to be a fruitful area of investigation that may shed light on the basic mechanisms of cognitive function and their therapeutic modulation.
登录
查看更多内容
影响因子：
3.2
作者：
Cicerone, Keith;Levin, Harvey;Whyte, John
通讯作者：
Whyte, John
影响因子：
3.4
作者：
Cattaneo, Zaira;Vecchi, Tomaso;Silvanto, Juha
通讯作者：
Silvanto, Juha
影响因子：
3.7
作者：
Cattaneo, Zaira;Rota, Federica;Silvanto, Juha
通讯作者：
Silvanto, Juha
影响因子：
--
作者：
Cotelli, Maria;Manenti, Rosa;Miniussi, Carlo
通讯作者：
Miniussi, Carlo
影响因子：
4.8
作者：
Cardenas-Morales, Lizbeth;Groen, Georg;Kammer, Thomas
通讯作者：
Kammer, Thomas