Effects of exercise amount and intensity versus a combined exercise and lifestyle intervention on metabolic syndrome in adults with prediabetes: a STRRIDE-PD randomized trial.
Effects of exercise amount and intensity versus a combined exercise and lifestyle intervention on metabolic syndrome in adults with prediabetes: a STRRIDE-PD randomized trial.
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DOI：
10.3389/fphys.2023.1199763
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发表时间：
2023
影响因子：
4
通讯作者：
Kraus, William E.
中科院分区：
文献类型：
--
作者：
Bennett, William C.;Collins, Katherine A.;Johnson, Johanna L.;Slentz, Cris A.;Willis, Leslie H.;Bales, Connie W.;Huffman, Kim M.;Kraus, William E.
关键词：
该次要分析的目的是确定糖尿病预防计划样干预对代谢综合征（MetS）的影响中有哪些部分可以单独通过运动来实现，以及确定运动强度和运动量对MetS总影响的相对重要性。久坐、超重的糖尿病前期成年人被随机分配到四种为期6个月的干预措施之一：1）低量/中等强度（50%峰值时10 kcal/kg/周）; 2）高剂量/中等强度（50%峰值时16 kcal/kg/周）; 3）高剂量/高强度（16 kcal/kg/周，75%峰值）;或4）饮食（7%体重减轻）加低量/中等强度（10 kcal/kg/周，50%峰值）。该次要分析的主要结局是MetS z评分的变化。共有130名参与者具有所有五项成人治疗小组（ATP）III MetS标准的完整数据。饮食和运动组在统计学上优于MetS z评分和ATP III评分。有氧运动单独达到饮食和运动联合干预对MetS评分总影响的24%-50%。在改善MetS评分方面，低量中等强度运动的定量表现等于或优于高量中等强度或高量剧烈强度运动的干预。饮食和运动联合干预在改善MetS z评分方面仍然更有效。然而，所有三种运动干预单独显示出改善代谢综合征z评分，这表明适量的中等强度运动是实现饮食和运动干预对代谢综合征影响的一半所需的。 临床试验注册：clinicaltrials.gov，标识符NCT 00962962。
The purpose of this secondary analysis was to determine what portion of the effects of a Diabetes Prevention Program-like intervention on metabolic syndrome (MetS) could be achieved with exercise alone, as well as to determine the relative importance of exercise intensity and amount to the total exercise effect on MetS. Sedentary, overweight adults with prediabetes were randomly assigned to one of four 6-month interventions: 1) low-amount/moderate-intensity (10 kcal/kg/week at 50% peak ); 2) high-amount/moderate-intensity (16 kcal/kg/week at 50% peak ); 3) high-amount/vigorous-intensity (16 kcal/kg/week at 75% peak ); or 4) diet (7% weight loss) plus low-amount/moderate-intensity (10 kcal/kg/week at 50% peak ). The primary outcome of this secondary analysis was change in the MetS z-score. A total of 130 participants had complete data for all five Adult Treatment Panel (ATP) III MetS criteria. The diet-and-exercise group statistically outperformed the MetS z-score and the ATP III score compared to the exercise alone group. Aerobic exercise alone achieved 24%–50% of the total effect of the combined diet-and-exercise intervention on the MetS score. Low-amount moderate-intensity exercise quantitatively performed equal to or better than the interventions of high-amount moderate-intensity or high-amount vigorous-intensity exercise in improving the MetS score. The combined diet-and-exercise intervention remains more efficacious in improving the MetS z-score. However, all three exercise interventions alone showed improvements in the MetS z-score, suggesting that a modest amount of moderate-intensity exercise is all that is required to achieve approximately half the effect of a diet-and-exercise intervention on the MetS. Clinical Trial Registration: clinicaltrials.gov, identifier NCT00962962.
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影响因子：
158.5
作者：
Knowler, WC;Barrett-Connor, E;Nathan, DM
通讯作者：
Nathan, DM
影响因子：
6.1
作者：
Kirwan JP;Sacks J;Nieuwoudt S
通讯作者：
Nieuwoudt S
DOI：
10.1007/978-981-15-1792-1_14
发表时间：
2020-01-01
期刊：
PHYSICAL EXERCISE FOR HUMAN HEALTH
影响因子：
--
作者：
Li, Guohua;Li, Jia;Gao, Feng
通讯作者：
Gao, Feng
影响因子：
3.3
作者：
Stensvold, Dorth;Tjonna, Arnt Erik;Slordahl, Stig Arild
通讯作者：
Slordahl, Stig Arild
影响因子：
2.8
作者：
Johnson, Johanna L.;Slentz, Cris A.;Kraus, William E.
通讯作者：
Kraus, William E.