Aspartame-True or False? Narrative Review of Safety Analysis of General Use in Products.
Aspartame-True or False? Narrative Review of Safety Analysis of General Use in Products.
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DOI：
10.3390/nu13061957
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发表时间：
2021-06-07
期刊：
影响因子：
5.9
通讯作者：
Szymański P
中科院分区：
文献类型：
--
作者：
Czarnecka K;Pilarz A;Rogut A;Maj P;Szymańska J;Olejnik Ł;Szymański P
阿斯巴甜是一种甜味剂，被引入以取代常用的蔗糖。它是由詹姆斯·M·施拉特于1965年发现的。它的甜度是蔗糖的180-200倍，预计它的摄入将降低发展中国家的肥胖率，并帮助那些与糖尿病作斗争的人。它主要用作软饮料、糖果和药品的甜味剂。尽管它被广泛使用，但它的安全性仍然存在争议。这篇叙述性的综述调查了关于阿斯巴甜的使用及其对人体的可能影响的现有文献，以提炼当前的知识。考虑到阿斯巴甜是一种广泛使用的人工甜味剂，继续安全性研究似乎是合适的。本文提到的研究总体上产生了非常有趣的结果，目前的综述突出了提供关于产品中存在的阿斯巴甜的可见和详细信息的社会问题。分析了阿斯巴甜对肥胖、糖尿病、儿童和胎儿、自闭症、神经变性、苯丙酮尿症、过敏和皮肤问题的影响，其致癌特性和遗传毒性。应该进行进一步的研究，以确保清楚地了解阿斯巴甜对健康的影响。
Aspartame is a sweetener introduced to replace the commonly used sucrose. It was discovered by James M. Schlatter in 1965. Being 180–200 times sweeter than sucrose, its intake was expected to reduce obesity rates in developing countries and help those struggling with diabetes. It is mainly used as a sweetener for soft drinks, confectionery, and medicines. Despite its widespread use, its safety remains controversial. This narrative review investigates the existing literature on the use of aspartame and its possible effects on the human body to refine current knowledge. Taking to account that aspartame is a widely used artificial sweetener, it seems appropriate to continue research on safety. Studies mentioned in this article have produced very interesting results overall, the current review highlights the social problem of providing visible and detailed information about the presence of aspartame in products. The studies involving the impact of aspartame on obesity, diabetes mellitus, children and fetus, autism, neurodegeneration, phenylketonuria, allergies and skin problems, its cancer properties and its genotoxicity were analyzed. Further research should be conducted to ensure clear information about the impact of aspartame on health.
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DOI：
10.1080/07315724.2005.10719449
发表时间：
2005-04-01
影响因子：
3.5
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DOI：
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