Loss of emotional insight in behavioral variant frontotemporal dementia or "frontal anosodiaphoria".
Loss of emotional insight in behavioral variant frontotemporal dementia or "frontal anosodiaphoria".
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DOI：
10.1016/j.concog.2011.09.005
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发表时间：
2011-12
影响因子：
2.4
通讯作者：
Shapira JS
中科院分区：
文献类型：
--
作者：
Mendez MF;Shapira JS
自知力丧失是行为变异额颞叶痴呆(BvFTD)的显著临床表现，但其特点尚不清楚。对12名bvFTD患者和12名阿尔茨海默病(AD)患者进行了结构化的认知洞察力(意识到有障碍)和情感洞察力(对有障碍的关注)的洞察力访谈。与AD患者相比，bvFTD患者较少意识和关注自己的疾病，他们对其对自己和对他人的影响的认识也较少。经过纠正反馈(“更新”)后，bvFTD患者与AD患者一样意识到自己的障碍，但仍然不关心和不了解其影响。这些发现表明，缺乏对bvFTD的洞察力并不是由于“病感失认症”，也不是由于认知和执行意识受损，而是因为“额叶失语”，即缺乏对bvFTD及其对自己和他人的影响的情感关注。
Loss of insight is a prominent clinical manifestation of behavioral variant frontotemporal dementia (bvFTD), but its characteristics are poorly understood. Twelve bvFTD patients were compared with 12 Alzheimer's disease (AD) patients on a structured insight interview of cognitive insight (awareness of having a disorder) and emotional insight (concern over having a disorder). Compared to the AD patients, the bvFTD patients were less aware and less concerned about their disorder, and they had less appreciation of its effects on themselves and on others. After corrective feedback (“updating”), the bvFTD patients were just as aware of their disorder as the AD patients but remained unconcerned and unappreciative of its effects. These findings suggest that lack of insight in bvFTD is not due to “anosognosia,” or impaired cognitive and executive awareness of disease, but to “frontal anosodiaphoria,” or lack of emotional concern over having bvFTD and its impact on themselves and others.
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DOI：
10.1176/appi.neuropsych.21.3.299
发表时间：
2009-06-01
影响因子：
2.9
作者：
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通讯作者：
Weintraub, Sandra
影响因子：
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作者：
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DOI：
10.1098/rstb.1998.0342
发表时间：
1998-11-29
影响因子：
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作者：
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通讯作者：
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影响因子：
3.4
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影响因子：
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