Suitability of measures of self-reported medication adherence for routine clinical use: a systematic review.

Suitability of measures of self-reported medication adherence for routine clinical use: a systematic review.
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DOI:
10.1186/1471-2288-11-149
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发表时间:
2011-11-03
影响因子:
4
通讯作者:
Willson A
Willson A
中科院分区:
医学3区
文献类型:
--
作者:
Garfield S;Clifford S;Eliasson L;Barber N;Willson A

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人们认识到有必要建立符合患者需求的初级保健用药依从性服务。要持续改进这类服务的质量,就需要有一种衡量遵守情况的常规工作方法,以便监测有效性。自我报告一直被认为是临床使用的选择方法;它便宜,相对不引人注目,能够区分故意和无意的不遵守,这有不同的潜在原因,因此需要不同的干预。在常规临床实践中使用的自我报告依从性测量最好是简短的、患者可以接受的、有效的、可靠的、有能力区分不同类型的不依从性,并能够在必要时由照顾者或与照顾者一起完成。我们系统地回顾了文献,以确定目前可用的适用于初级保健的自我报告依从性措施,并评估它们在多大程度上符合上述标准。我们检索了Medline、Embase、International Pharmtics Abstrates、Pharmline、CINAHL、QicINFO和HAPI数据库,以确定报告仿制药依从性措施的发展、验证或可靠性的研究。一名评审员筛选了所有摘要,并对获得的所有相关全文文章进行了评估,另一名评审员筛选/评估了10%,以检查可靠性。确定了58项措施。虽然提供了验证数据以支持绝大多数自我报告的措施(54/58),但提供了相对较少数量的措施的数据用于可靠性(16/58)和完成时间(3/58)。很少有人被设计为有能力由照顾者完成或与照顾者一起完成,也很少有人能够区分不同类型的不遵守,这限制了他们有效地用于持续改进有针对性的提高遵守干预措施的能力。现有的数据表明,患者发现估计总体依从性比报告错过的具体剂量更容易。视觉模拟秤对患者来说比其他类型的秤更容易,但不适合电话管理。需要一种可用于遵守服务的常规持续质量监控的措施。
There is a recognised need to build primary care medication adherence services which are tailored to patients' needs. Continuous quality improvement of such services requires a regular working method of measuring adherence in order to monitor effectiveness. Self report has been considered the method of choice for clinical use; it is cheap, relatively unobtrusive and able to distinguish between intentional and unintentional non-adherence, which have different underlying causes and therefore require different interventions. A self report adherence measure used in routine clinical practice would ideally be brief, acceptable to patients, valid, reliable, have the ability to distinguish between different types of non-adherence and be able to be completed by or in conjunction with carers where necessary. We systematically reviewed the literature in order to identify self report adherence measures currently available which are suitable for primary care and evaluate the extent to which they met the criteria described above. We searched the databases Medline, Embase, International Pharmaceutical Abstracts, Pharmline, CINAHL, PsycINFO and HaPI to identify studies reporting the development, validation or reliability of generic adherence measures. One reviewer screened all abstracts and assessed all relevant full text articles obtained and a second reviewer screened/assessed 10% to check reliability. Fifty eight measures were identified. While validation data were presented in support of the vast majority of self reported measures (54/58), data for a relatively small number of measures was presented for reliability (16/58) and time to complete (3/58). Few were designed to have the ability to be completed by or in conjunction with carers and few were able to distinguish between different types of non-adherence, which limited their ability be used effectively in the continuous improvement of targeted adherence enhancing interventions. The data available suggested that patients find it easier to estimate general adherence than to report a specific number of doses missed. Visual analogue scales can be easier for patients than other types of scale but are not suitable for telephone administration. There is a need for a measure which can be used in the routine continual quality monitoring of adherence services.
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发表时间: 2004-03-01
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