Anti-Inflammatory Dietary Diversity and Depressive Symptoms among Older Adults: A Nationwide Cross-Sectional Analysis.

Anti-Inflammatory Dietary Diversity and Depressive Symptoms among Older Adults: A Nationwide Cross-Sectional Analysis.
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老年人的抗炎饮食多样性和抑郁症状:全国横断面分析

DOI:
10.3390/nu14235062
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发表时间:
2022-11-28
期刊:
影响因子:
5.9
通讯作者:
Yao Y
Yao Y
中科院分区:
医学2区
文献类型:
--
作者:
Lv X;Sun S;Wang J;Chen H;Li S;Hu Y;Yu M;Zeng Y;Gao X;Xu Y;Yao Y

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本研究的目的是将全国范围内的中国老年人样本中的抗炎饮食多样性与抑郁症状联系起来。我们使用了2018年中国纵向健康长寿调查(CLHLS)的数据。我们使用流行病学研究中心抑郁量表(CES-D-10)的10个项目来评估抑郁症状。基于先前研究产生的膳食多样性指数(DDI),我们构建了两个新的指标:富含蛋白质的膳食多样性指数饮食(PEDDI)和抗炎膳食多样性指数饮食(AIDDI)。我们使用多变量逻辑模型来评估 DDI、PEDDI 和 AIDDI 与抑郁症状的关联,并针对一系列潜在的混杂因素进行了统计调整。分析共有 12,192 名参与者(平均年龄 83.6 岁)。我们发现,DDI(OR = 0.91,95% CI:0.89–0.92)和 PEDDI(OR = 0.91,95% CI:0.88–0.93)得分较高的参与者出现抑郁症状的几率较低,而 AIDDI 与抑郁症状之间的关联更为显着(OR = 0.80,95% CI: 0.78–0.83)。这些关联仍然存在于亚组分析和敏感性分析中。结果表明,摄入多样化的饮食,特别是抗炎食物,可能与降低抑郁症状的风险有关。这项研究的结果如果被证实是因果关系,则提供证据表明,采取抗炎多样化饮食的干预措施可能会减轻老年人的抑郁症负担。
The purpose of this study was to associate the anti-inflammatory dietary diversity and depressive symptoms among a nationwide sample of Chinese older adults. We used data from the 2018 wave of Chinese longitudinal healthy longevity survey (CLHLS). We assessed depressive symptoms using the 10 items of the center for epidemiologic studies depression scale (CES-D-10). Based on the dietary diversity index (DDI) generated by previous studies, we construct two novel indicators: the protein-enriched dietary diversity index diet (PEDDI) and the anti-inflammatory dietary diversity index diet (AIDDI). We used multivariate logistic models to evaluate the associations of DDI, PEDDI, and AIDDI with depressive symptoms, statistically adjusted for a range of potential confounders. A total of 12,192 participants (mean age 83.6 years) were included in the analysis. We found that participants with a higher score of DDI (OR = 0.91, 95% CI: 0.89–0.92) and PEDDI (OR = 0.91, 95% CI: 0.88–0.93) showed lower odds of having depressive symptoms, while the association between AIDDI and depressive symptoms was more marked (OR = 0.80, 95% CI: 0.78–0.83). The associations remained in subgroup analyses and sensitivity analyses. The results indicate that intaking diversified diet, particularly anti-inflammatory foods, may be associated with a lower risk of depressive symptoms. The findings of this study, if confirmed as causal, provide evidence that an intervention of adopting an anti-inflammatory diversified diet may reduce the burden of depression among older adults.
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