Clinical evidence that the pandemic from 1889 to 1891 commonly called the Russian flu might have been an earlier coronavirus pandemic.
Clinical evidence that the pandemic from 1889 to 1891 commonly called the Russian flu might have been an earlier coronavirus pandemic.
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DOI：
10.1111/1751-7915.13889
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发表时间：
2021-09
影响因子：
5.7
通讯作者：
Brüssow L
中科院分区：
文献类型：
--
作者：
Brüssow H;Brüssow L
来自英国和德国的当代医学报告显示，1889年至1891年期间发生的大流行感染（历史上被称为俄罗斯流感）患者与COVID-19有许多共同特征。最值得注意的是多系统影响方面，包括呼吸道、胃肠道和神经系统症状，包括味觉和嗅觉丧失;恢复时间延长，类似于长时间的新冠肺炎和多器官血栓形成、炎症和风湿性影响的病理学观察。与COVID-19不同，与流感不同，老年受试者的死亡率较高，而儿童仅受到轻微影响。当代报告指出，宠物动物或马与人类之间的跨种感染，这将与广泛宿主范围的牛冠状病毒交叉感染一致，通过分子钟参数可追溯到约1890年的跨种感染事件。对1889年至1891年俄罗斯流感大流行患者的当代临床报告显示出与COVID-19患者惊人的相似性，表现出呼吸道，肠道和神经系统的多器官影响，嗅觉和味觉的丧失，以及疾病症状持续时间长。
Contemporary medical reports from Britain and Germany on patients suffering from a pandemic infection between 1889 and 1891, which was historically referred to as the Russian flu, share a number of characteristics with COVID‐19. Most notable are aspects of multisystem affections comprising respiratory, gastrointestinal and neurological symptoms including loss of taste and smell perception; a protracted recovery resembling long covid and pathology observations of thrombosis in multiple organs, inflammation and rheumatic affections. As in COVID‐19 and unlike in influenza, mortality was seen in elderly subjects while children were only weakly affected. Contemporary reports noted trans‐species infection between pet animals or horses and humans, which would concur with a cross‐infection by a broad host range bovine coronavirus dated by molecular clock arguments to an about 1890 cross‐species infection event. Contemporary clinical reports on patients of the Russian flu pandemic of 1889 to 1891 show striking similarity to COVID‐19 patients, demonstrating *multiorgan affections of the respiratory, intestinal and neural system, *loss of smell and taste, *and long disease symptom duration.
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影响因子：
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