Birth characteristics and brain cancers in young children.
Birth characteristics and brain cancers in young children.
复制标题
幼儿的出生特征和脑癌。
DOI:
10.1093/ije/dyg057
复制
发表时间:
2003
影响因子:
7.7
通讯作者:
Reynolds,Peggy
中科院分区:
文献类型:
--
作者:
VonBehren,Julie;Reynolds,Peggy
BackgroundHigh birthweight is a potential risk factor for childhood brain tumours, particularly astrocytomas. We investigated several birth characteristics in relationship to brain cancers in young children.MethodsWe obtained 849 invasive central nervous system (CNS) cancer cases, ages 0–4 years, from California’s population-based cancer registry for 1988–1997. We matched 746 (88%) of these cases to a California live birth certificate. We randomly selected two control birth certificates for each case, matched on date of birth and gender. We used conditional logistic regression to obtain odds ratios (OR) and 95% CI. The birth characteristics examined included birthweight, gestational age, race, parental age, and parental education.ResultsAnalysing all CNS tumours combined, we found that children of other racial/ ethnic groups had OR below one compared with non-Hispanic white children. When adjusted for gestational age, race/ethnicity, and mother’s place of birth, the OR for high birthweight (⩾4000 g) was 1.05 (95% CI: 0.79–1.38) compared with children with birthweights of 2500–3999 g. For astrocytomas (313 cases), the adjusted OR for high birthweight was 1.40 (95% CI: 0.90–2.18). When parental education was included in the model (available for only a subset of the birth years), the adjusted OR was 1.71 (95% CI: 1.01–2.90). High birthweight did not appear to be a risk factor for primitive neuroectodermal tumours (PNET).ConclusionsWe found high birthweight associated with increased risk of astrocytomas, but not PNET, in young children.
登录
查看更多内容
影响因子:
6.4
作者:
M. Mccredie;P. Maisonneuve;P. Boyle
通讯作者:
P. Boyle
DOI:
--
发表时间:
1992
期刊:
The British journal of cancer. Supplement
影响因子:
--
作者:
J. Birch;V. Blair
通讯作者:
V. Blair
影响因子:
8.8
作者:
PA McKinney;JW Ironside;EF Harkness;JC Arango;D. Doyle;RJ Black
通讯作者:
RJ Black
DOI:
10.1016/s0022-3476(97)70091-x
发表时间:
1997
期刊:
The Journal of pediatrics
影响因子:
--
作者:
Yeazel,MW;Ross,JA;Buckley,JD;Woods,WG;Ruccione,K;Robison,LL
通讯作者:
Robison,LL
DOI:
10.1093/jnci/90.17.1269
发表时间:
1998-09-02
期刊:
JOURNAL OF THE NATIONAL CANCER INSTITUTE
影响因子:
--
作者:
Smith, MA;Freidlin, B;Simon, R
通讯作者:
Simon, R