Non-stimulus-evoked activity as a measure of neural noise in the frequency-following response.
Non-stimulus-evoked activity as a measure of neural noise in the frequency-following response.
复制标题
DOI：
10.1016/j.jneumeth.2021.109290
复制
发表时间：
2021-10-01
影响因子：
3
通讯作者：
Kraus N
中科院分区：
文献类型：
--
作者：
Krizman J;Bonacina S;Otto-Meyer R;Kraus N
频率跟随响应（FFR）是一种神经生理学响应，可捕捉声音处理的不同方面。与所有诱发反应一样，FFR 在采集过程中容易受到电噪声和肌源性噪声的污染。点击诱发听觉脑干反应收集标准已用于 FFR 收集，然而，这些标准是否足以限制 FFR 噪声污染尚不清楚。因此，一个关键问题仍然存在：不同的 FFR 分量在多大程度上反映了噪声污染？这与刺激前幅度（即诱发反应之前的活动）尤其相关，因为该测量已用于索引噪声污染和神经噪声。我们进行了两个实验。首先，使用> 1000个年轻成人FFR，我们进行回归以确定由肌源性和电噪声解释的方差，如每个FFR组件上的伪影抑制计数和电极阻抗所索引的。其次，我们重新分析了运动经验和社会经济地位造成的刺激前振幅差异，添加了伪影排斥和阻抗的协变量。我们发现非神经噪声对 FFR 成分的贡献很小，并且无法解释刺激前幅度的群体差异。刺激前幅度被认为是非神经噪声污染的衡量标准。然而，非神经噪声并不是造成该测量差异的唯一因素，并且不能解释群体差异。两个实验的结果表明，非神经噪声对 FFR 分量的影响很小，并且不会掩盖 FFR 的个体差异，而且刺激前幅度会影响神经噪声。
The frequency-following response, or FFR, is a neurophysiologic response that captures distinct aspects of sound processing. Like all evoked responses, FFR is susceptible to electric and myogenic noise contamination during collection. Click-evoked auditory brainstem response collection standards have been adopted for FFR collection, however, whether these standards sufficiently limit FFR noise contamination is unknown. Thus, a critical question remains: to what extent do distinct FFR components reflect noise contamination? This is especially relevant for prestimulus amplitude (i.e., activity preceding the evoked response), as this measure has been used to index both noise contamination and neural noise. We performed two experiments. First, using >1000 young-adult FFRs, we ran regressions to determine the variance explained by myogenic and electrical noise, as indexed by artifact rejection count and electrode impedance, on each FFR component. Second, we reanalyzed prestimulus amplitude differences attributed to athletic experience and socioeconomic status, adding covariates of artifact rejection and impedance. We found that non-neural noise marginally contributed to FFR components and could not explain group differences on prestimulus amplitude. Prestimulus amplitude has been considered a measure of non-neural noise contamination. However, non-neural noise was not the sole contributor to variance in this measure and did not explain group differences. Results from the two experiments suggest that the effects of non-neural noise on FFR components are minimal and do not obscure individual differences in the FFR and that prestimulus amplitude indexes neural noise.
登录
查看更多内容
MEG揭示的对听觉频率遵循响应的皮质贡献。
影响因子：
16.6
作者：
Coffey EB;Herholz SC;Chepesiuk AM;Baillet S;Zatorre RJ
通讯作者：
Zatorre RJ
DOI：
10.1016/j.clinph.2015.01.026
发表时间：
2015-12
期刊：
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
影响因子：
--
作者：
Krizman J;Tierney A;Fitzroy AB;Skoe E;Amar J;Kraus N
通讯作者：
Kraus N
影响因子：
2.4
作者：
KLATT, DH
通讯作者：
KLATT, DH
影响因子：
16.6
作者：
Coffey, Emily B. J.;Nicol, Trent;Kraus, Nina
通讯作者：
Kraus, Nina
影响因子：
2.8
作者：
Krizman, Jennifer;Bonacina, Silvia;Kraus, Nina
通讯作者：
Kraus, Nina