Hurtful words: association of exposure to peer verbal abuse with elevated psychiatric symptom scores and corpus callosum abnormalities.
Hurtful words: association of exposure to peer verbal abuse with elevated psychiatric symptom scores and corpus callosum abnormalities.
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DOI：
10.1176/appi.ajp.2010.10010030
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发表时间：
2010-12
期刊：
影响因子：
--
通讯作者：
McGreenery CE
中科院分区：
文献类型：
--
作者：
Teicher MH;Samson JA;Sheu YS;Polcari A;McGreenery CE
先前的研究表明，在儿童时期暴露于父母的言语虐待（VA）与成人精神病理学和大脑结构改变的比率较高有关。在这里，我们研究的潜在后果暴露于同龄人VA在童年时期。共有848名没有家庭暴力、性虐待或父母身体虐待史的年轻人（年龄在18至25岁之间）对他们童年时期接触父母和同伴VA的情况进行了评估，并完成了一份自我报告，其中包括Kellner症状问卷、边缘系统症状检查表-33和分离体验量表。扩散张量图像收集的一个子集的63名年轻人没有滥用或暴露于父母VA的历史，选择不同程度的暴露于同龄人VA。图像进行了分析，使用道为基础的空间统计分析的协方差分析显示“剂量依赖性”的影响，同伴VA焦虑，抑郁，愤怒，敌意，解离，“边缘易怒”，和药物使用。同龄人和父母的VA基本上是等效的效果大小对这些评级。通径分析显示，初中阶段的同伴VA对症状得分的影响最为显著。暴露于同伴VA的程度与胼胝体和辐射冠的平均和径向扩散率增加和各向异性分数降低相关。这些研究结果平行与儿童期暴露于父母VA相关的精神病理学以前的报告，并支持这一假设，即暴露于同龄人VA是一种令人厌恶的刺激与增加的症状评分和有意义的改变，在大脑结构。
Previous studies have shown that exposure to parental verbal abuse (VA) in childhood was associated with higher rates of adult psychopathology and alterations in brain structure. Here we examine the potential consequences of exposure to peer VA during childhood. A total of 848 young adults (ages 18 to 25 years) with no history of exposure to domestic violence, sexual abuse, or parental physical abuse rated their childhood exposure to parental and peer VA and completed a self-report packet that included the Kellner Symptom Questionnaire, the Limbic Symptom Checklist-33, and the Dissociative Experiences Scale. Diffusion tensor images were collected on a subset of 63 young adults with no history of abuse or exposure to parental VA selected for varying degrees of exposure to peer VA. Images were analyzed using tract based spatial statistics Analysis of covariance revealed ‘dose-dependent’ effects of peer VA on anxiety, depression, anger-hostility, dissociation, ‘limbic irritability’, and drug use. Peer and parental VA were essentially equivalent in effect size on these ratings. Path analysis indicated that peer VA during middle school years had the most significant effect on symptom scores. Degree of exposure to peer VA correlated with increased mean and radial diffusivity and decreased fractional anisotropy in corpus callosum and corona radiata. These findings parallel previous reports of psychopathology associated with childhood exposure to parental VA, and support the hypothesis that exposure to peer VA is an aversive stimulus associated with increased symptom ratings and meaningful alterations in brain structure.
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影响因子：
3.4
作者：
Brubaker CJ;Schmithorst VJ;Haynes EN;Dietrich KN;Egelhoff JC;Lindquist DM;Lanphear BP;Cecil KM
通讯作者：
Cecil KM
影响因子：
1.9
作者：
BERNSTEIN, EM;PUTNAM, FW
通讯作者：
PUTNAM, FW
暴露于父母言语虐待的年轻人中白质异常的初步证据。
影响因子：
10.6
作者：
Choi, Jeewook;Jeong, Bumseok;Rohan, Michael L.;Polcari, Ann M.;Teicher, Martin H.
通讯作者：
Teicher, Martin H.
影响因子：
17.7
作者：
MacMillan, HL;Fleming, JE;Beardslee, WR
通讯作者：
Beardslee, WR
影响因子：
3.3
作者：
Reese, TG;Heid, O;Wedeen, VJ
通讯作者：
Wedeen, VJ