Sex Moderates the Relationship That Number of Professional Fights Has With Cognition and Brain Volumes.
Sex Moderates the Relationship That Number of Professional Fights Has With Cognition and Brain Volumes.
复制标题
DOI：
10.3389/fneur.2020.574458
复制
发表时间：
2020
影响因子：
3.4
通讯作者：
Banks SJ
中科院分区：
文献类型：
--
作者：
Bennett LL;Stephen SJ;Bernick C;Shan G;Banks SJ
目的：在所有运动项目中，女性脑震荡的发病率和症状报告都更高。虽然大脑结构变化和认知能力下降与重复性头部撞击（RHI）有关，但性别的作用尚未得到很好的理解。本研究旨在确定在一组拳击手、混合武术运动员和武术运动员中，性别对职业拳击比赛次数与认知功能和区域脑容量之间的关系是否有调节作用。方法：根据年龄、受教育年限、种族和战斗方式，将55名女性和55名男性配对。通过CNS生命体征计算机化认知组合和补充措施评估认知。还考虑了结构性脑扫描、人口统计数据和职业拳击次数（NoPF）。通过协方差分析比较匹配对，占总脑体积。利用受试者内调节模型评估性别对NoPF与脑容量和认知表现之间关系的调节作用。结果：与女性相比，男性在心理速度方面的表现较差。在一系列评估性别作为NoPF和区域脑容量/认知表现之间关系的调节剂的分析中，在认知功能的多个测量中观察到显着的调节效应，例如男性表现较差。还观察到许多区域脑容量的差异，例如NoPF和脑容量之间的关系在男性中更陡峭。结论：性别被认为是一个重要的主持人之间的关系NoPF，认知功能方面，和大量的大脑区域，这表明性别差异的神经解剖和认知反应RHI值得进一步关注。
Objective: Incidence of concussions and report of symptoms are greater among women across sports. While structural brain changes and cognitive declines are associated with repetitive head impact (RHI), the role of sex is not well-understood. This study aimed to determine if there is a moderating effect of sex on the relationship the number of professional fights has with cognitive functioning and regional brain volumes in a cohort of boxers, mixed martial artists, and martial artists. Methods: A total of 55 women were matched with 55 men based on age, years of education, ethnicity, and fighting style. Cognition was assessed via the CNS Vital Signs computerized cognitive battery and supplemental measures. Structural brain scans, demographic data, and number of professional fights (NoPF) were also considered. The matched pairs were compared via analysis of covariance, accounting for total brain volume. Within-subject moderation models were utilized to assess the moderating effect of sex on the relationship between NoPF and brain volumes and cognitive performance. Results: Men were observed to have poorer performance on measures of psychomotor speed when compared to women. On a series of analyses assessing the role of sex as a moderator of the relationship between NoPF and regional brain volumes/cognitive performance, a significant moderation effect was observed across multiple measures of cognitive functioning, such that men had poorer performance. Differences in numerous regional brain volumes were also observed, such that the relationship between NoPF and brain volumes was steeper among men. Conclusion: Sex was observed to be an important moderator in the relationship between NoPF, aspects of cognitive functioning, and volumes of numerous brain regions, suggesting that sex differences in neuroanatomic and cognitive response to RHI deserve further attention.
登录
查看更多内容
影响因子：
4.8
作者：
Iscan Z;Jin TB;Kendrick A;Szeglin B;Lu H;Trivedi M;Fava M;McGrath PJ;Weissman M;Kurian BT;Adams P;Weyandt S;Toups M;Carmody T;McInnis M;Cusin C;Cooper C;Oquendo MA;Parsey RV;DeLorenzo C
通讯作者：
DeLorenzo C
影响因子：
3.3
作者：
Covassin, Tracey;Moran, Ryan;Elbin, R. J.
通讯作者：
Elbin, R. J.
影响因子：
5
作者：
Bernick, Charles;Banks, Sarah;Modic, Michael
通讯作者：
Modic, Michael
影响因子：
1.7
作者：
Iverson, Grant L.;Brooks, Brian L.;Rennison, V. Lynn Ashton
通讯作者：
Rennison, V. Lynn Ashton
影响因子：
18.4
作者：
Bernick C;Banks SJ;Shin W;Obuchowski N;Butler S;Noback M;Phillips M;Lowe M;Jones S;Modic M
通讯作者：
Modic M