Risk of preterm delivery in non-diabetic women with polycystic ovarian syndrome.
Risk of preterm delivery in non-diabetic women with polycystic ovarian syndrome.
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DOI：
10.1038/jp.2011.194
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发表时间：
2012-10
影响因子：
2.9
通讯作者：
Lo, J. C.
中科院分区：
文献类型：
--
作者：
Yamamoto, M.;Feigenbaum, S. L.;Crites, Y.;Escobar, G. J.;Yang, J.;Ferrara, A.;Lo, J. C.
探讨多囊卵巢综合征（PCOS）妇女早产的风险和病因。回顾性队列研究比较非糖尿病PCOS和非PCOS单胎妊娠妇女的早产率多变量逻辑回归分析用于确定PCOS妇女早产的预测因素。在908例单胎妊娠的PCOS妇女中，早产率为12.9%，而非PCOS妇女为7.4%（p<0.01）。PCOS妇女早产的原因包括早产（41%），宫颈机能不全（11%），高血压并发症（20%），早产胎膜早破（15%），胎儿-胎盘问题（9%）和宫内胎儿死亡（5%）。母亲年龄、种族/民族和未经产是PCOS早产的重要预测因素，而体重指数和生育药物则不是。与非PCOS妇女相比，PCOS妇女早产的比例更高（12.9%），大多数病例是由于自发性早产。未来的研究应探讨病因和改善PCOS妊娠结局的策略。
To examine the risk and etiology of preterm delivery in women with polycystic ovary syndrome (PCOS). Retrospective cohort study comparing preterm delivery rate among non-diabetic PCOS and non-PCOS women with singleton pregnancy. Multivariable logistic regression was used to identify predictors of preterm delivery among PCOS women. Among 908 PCOS women with singleton pregnancy, 12.9% delivered preterm compared to 7.4% among non-PCOS women (p<0.01). Causes of preterm delivery among PCOS women included preterm labor (41%), cervical insufficiency (11%), hypertensive complications (20%), preterm premature rupture of membranes (15%), fetal-placental concerns (9%) and intrauterine fetal demise (5%). Maternal age, race/ethnicity and nulliparity were significant predictors of preterm delivery in PCOS, while body mass index and fertility medications were not. A higher proportion of PCOS women delivered preterm (12.9%) compared to non-PCOS women, with the majority of cases due to spontaneous preterm birth. Future studies should explore etiologies and strategies to improve pregnancy outcomes in PCOS.
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DOI：
10.1111/j.1365-2362.2006.01712.x
发表时间：
2006-10-01
影响因子：
5.5
作者：
Diamanti-Kandarakis, E.;Alexandraki, K.;Panidis, D.
通讯作者：
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影响因子：
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DOI：
10.1111/j.1471-0528.2005.00598.x
发表时间：
2005-03-01
影响因子：
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作者：
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影响因子：
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作者：
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作者：
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