Self-referenced processing, neurodevelopment and joint attention in autism.

Self-referenced processing, neurodevelopment and joint attention in autism.
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DOI:
10.1177/1362361310366315
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发表时间:
2010-09
期刊:
Autism : the international journal of research and practice
影响因子:
--
通讯作者:
Henderson H
Henderson H
中科院分区:
其他
文献类型:
--
作者:
Mundy P;Gwaltney M;Henderson H

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本文描述了一种联合注意力、自参考处理和自闭症的并行分布式处理模型(PDPM)。根据这个模型,自闭症涉及快速、综合处理自我参照(本体感受和内感受)和其他参照(外感受)信息的能力的早期损伤。事实证明,联合注意力的测量在自闭症研究中是有用的,因为它们对自我和其他参考刺激的“并行”和综合处理的早期发展很敏感。此外,联合注意行为是结果,也是远端分布式皮质系统功能发展的组织者,涉及包括前额叶和岛叶皮质的前部网络,以及包括颞叶和顶叶皮质的后部神经网络。联合注意力的测量提供了自闭症并行和分布式处理系统中非典型发展的早期行为指标。此外,有人提出,整合自我和他人参考信息的能力的早期、慢性障碍可能会对自闭症患者自我意识的发展产生连锁反应。讨论了该模型的假设、实证支持和未来研究意义。
This article describes a parallel and distributed processing model (PDPM) of joint attention, self-referenced processing and autism. According to this model, autism involves early impairments in the capacity for rapid, integrated processing of self-referenced (proprioceptive and interoceptive) and other-referenced (exteroceptive) information. Measures of joint attention have proven useful in research on autism because they are sensitive to the early development of the ‘parallel’ and integrated processing of self- and other-referenced stimuli. Moreover, joint attention behaviors are a consequence, but also an organizer of the functional development of a distal distributed cortical system involving anterior networks including the prefrontal and insula cortices, as well as posterior neural networks including the temporal and parietal cortices. Measures of joint attention provide early behavioral indicators of atypical development in this parallel and distributed processing system in autism. In addition it is proposed that an early, chronic disturbance in the capacity for integrating self- and other-referenced information may have cascading effects on the development of self awareness in autism. The assumptions, empirical support and future research implications of this model are discussed.
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