Effects of prolonged exercise on puberty and luteinizing hormone secretion in female rats.
Effects of prolonged exercise on puberty and luteinizing hormone secretion in female rats.
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长时间运动对雌性大鼠青春期和黄体生成素分泌的影响。
DOI：
10.1152/ajpregu.1989.257.6.r1359
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Bronson,FH
中科院分区：
文献类型：
--
作者：
Manning,JM;Bronson,FH
未成熟的雌性大鼠需要长时间奔跑以获得食物。他们获得的食物量足以在非工作条件下完成青春期发育和适度生长，但这两个过程都被运动要求所阻碍。长时间的运动也阻止了黄体生成素（LH）的脉冲式释放，只有两个LH脉冲，在7个运动的女性在8周的年龄，共24小时的监测。相比之下，在青春期后，正常生长的女性在发情后期相同的年龄几乎1脉冲/小时。当运动雌鼠在8周龄时放松对跑步的要求时，它们经历了快速的追赶生长和生殖发育。基础分泌和LH脉冲频率在48 h内显著增加，这些雌性中的大多数在松弛后的第三个黑暗期排卵。总之，这里采用的实验范式和技术产生高度可预测的结果，他们应该证明是有用的探索其他神经内分泌途径，通过过度运动拮抗生殖。
Immature female rats were required to run for prolonged periods of time to obtain food. The amount of food they earned was adequate for full pubertal development and moderate growth under nonworking conditions, but both processes were blocked by the exercise requirement. Prolonged exercise also blocked the pulsatile release of luteinizing hormone (LH); only two LH pulses were seen in seven exercising females during a total of 24 h of monitoring at 8 wk of age. By comparison, almost 1 pulse/h was seen in postpubertal, normally growing females of this same age during metestrus. When the exercising females' running requirement was relaxed at 8 wk of age they experienced rapid catch-up growth and reproductive development. Both basal secretion and LH pulse frequency increased markedly within 48 h, and most of these females ovulated during the third dark period after relaxation. Altogether, the experimental paradigm and techniques employed here yield highly predictable results, and they should prove useful for exploring other neuroendocrine pathways through which excessive exercise antagonizes reproduction.
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影响因子：
11.2
作者：
SPENCER, SS;SPENCER, DD;MATTSON, RH
通讯作者：
MATTSON, RH
影响因子：
5.3
作者：
BRAZIER, MAB
通讯作者：
BRAZIER, MAB
人类癫痫发作的光谱分析。
DOI：
10.1016/0010-4809(75)90023-3
发表时间：
1975
期刊：
Computers and biomedical research, an international journal
影响因子：
--
作者：
B. Tharp;W. Gersch
通讯作者：
W. Gersch
癫痫病灶的自动检测和定位。
DOI：
10.1016/0013-4694(77)90189-4
发表时间：
1977
期刊：
Electroencephalography and clinical neurophysiology
影响因子：
--
作者：
F. H. Lopes da Silva;K. van Hulten;J. Lommen;W. Storm van Leeuwen;C.W.M. van Veelen;W. Vliegenthart
通讯作者：
W. Vliegenthart
影响因子：
4.7
作者：
van Klink, N. E. C.;van't Klooster, M. A.;Zijlmans, M.
通讯作者：
Zijlmans, M.