Ecological factors influence balancing selection on leaf chemical profiles of a wildflower.
Ecological factors influence balancing selection on leaf chemical profiles of a wildflower.
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生态因子影响野花叶片化学组成的平衡选择。
DOI：
10.1038/s41559-021-01486-0
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发表时间：
2021-08
影响因子：
16.8
通讯作者：
Mitchell-Olds T
中科院分区：
文献类型：
--
作者：
Carley LN;Mojica JP;Wang B;Chen CY;Lin YP;Prasad KVSK;Chan E;Hsu CW;Keith R;Nuñez CL;Olson-Manning CF;Rushworth CA;Wagner MR;Wang J;Yeh PM;Reichelt M;Ghattas K;Gershenzon J;Lee CR;Mitchell-Olds T
平衡选择经常被认为是维持种群内和种群间变异的一种机制。然而，很少有例子表明，平衡选择操作的基因座基础的复杂性状，往往表现出高水平的变异。我们研究了一种多年生野花（芸苔科，Boechera stricta）的局部多态性——叶片化学特征——可能维持变异的机制，明确询问了多种生态和遗传过程，包括选择的空间变异、拮抗多效性和频率依赖选择。一套普通的花园和温室实验表明，化学特征变异的等位基因在不同环境下具有不同的适合度效应，这暗示了化学特征选择的两个生态驱动因素：草食和干旱。表型-环境关联和分子遗传分析揭示了这些驱动因素过去选择的额外证据。综上所述，这些数据与化学剖面的平衡选择一致，这可能是由于次生化学生物合成基因对草食动物防御和干旱响应的多效性作用所致。平衡选择作用于控制复杂性状的基因座的证据是有限的。在这里，作者展示了多年生野花的化学特征在过去的选择中受到两种生态驱动因素的影响，草食和干旱，这与该性状的平衡选择一致。
Balancing selection is frequently invoked as a mechanism that maintains variation within and across populations. However, there are few examples of balancing selection operating on loci underpinning complex traits, which frequently display high levels of variation. We investigated mechanisms that may maintain variation in a focal polymorphism—leaf chemical profiles of a perennial wildflower (Boechera stricta, Brassicaceae)—explicitly interrogating multiple ecological and genetic processes including spatial variation in selection, antagonistic pleiotropy, and frequency-dependent selection. A suite of common garden and greenhouse experiments showed that the alleles underlying variation in chemical profile have contrasting fitness effects across environments, implicating two ecological drivers of selection on chemical profile: herbivory and drought. Phenotype-environment associations and molecular genetic analyses revealed additional evidence of past selection by these drivers. Together, these data are consistent with balancing selection on chemical profile, likely caused by pleiotropic effects of secondary chemical biosynthesis genes on herbivore defense and drought response. Evidence for balancing selection acting on loci that control complex traits is limited. Here, the authors show evidence for past selection on chemical profile in a perennial wildflower by two ecological drivers, herbivory and drought, consistent with balancing selection on this trait.
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影响因子：
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通讯作者：
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