Gonadogenesis in Pristionchus pacificus and organ evolution: development, adult morphology and cell-cell interactions in the hermaphrodite gonad.
Gonadogenesis in Pristionchus pacificus and organ evolution: development, adult morphology and cell-cell interactions in the hermaphrodite gonad.
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太平洋原虫的性腺发生和器官进化：雌雄同体性腺的发育、成体形态和细胞间相互作用。
DOI：
10.1016/j.ydbio.2004.09.021
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发表时间：
2005
影响因子：
2.7
通讯作者：
R. Sommer
中科院分区：
文献类型：
--
作者：
D. Rudel;Metta Riebesell;R. Sommer
线虫性腺是研究器官发生和发育与细胞生物学基本问题的典型系统。线虫生殖腺在物种之间变化很大（Chitwood，B.G.，Chitwood，M.B.，1950.介绍线虫学。”大学公园出版社，巴尔的摩; Felix，M.A.，斯滕贝格，P.W.，1996.线虫单臂性腺发育中的对称性破坏。Development 122，2129-2142）。因此，性腺发生的比较发育生物学提供了研究导致新器官形态的发育和细胞过程变化的可能性，从而可以深入了解这些变化如何影响动物baupläne。太平洋棱纹线虫（英语：Pristionchus pacificus）是一种自由生活的线虫，约在2亿至3亿年前从模式线虫秀丽隐杆线虫（英语：Causophabditis elegans）分化而来。在形态和发育方面，太平洋对虾与中国对虾具有高度的同源性。优美的然而，形态学和潜在的分子信号网络的许多差异很容易识别，使太平洋假单胞菌成为比较方法的理想选择。在这里，我们报告了一个详细的描述P. pacificus雌雄同体性腺使用电子和荧光显微镜，这将提供一个基础的遗传突变的表型研究和在体内的克隆基因的分子研究参与P. pacificus性腺发育。本文报道了太平洋真鲷性腺的形态与中国真鲷不同。优美的这些差异包括生殖系模式差异、异时差异、新的性腺臂迁移、一些体细胞组织的新细胞组成（例如，构成鞘和不同受精囊区域的细胞数目不同），体细胞组织的缺乏（例如，受精囊瓣细胞），鞘的新结构，以及单个鞘细胞的细胞和亚细胞形态的变化。此外，我们报告了一组细胞消融在太平洋对虾，表明广泛的细胞之间的沟通体细胞性腺组织和生殖系。太平洋对虾个体消融实验表明，个体体组织对生殖系模式化的影响与C。优美的
The nematode gonad is an exemplary system for the study of organogenesis and fundamental problems in developmental and cellular biology. Nematode gonads vary dramatically across species (Chitwood, B.G., Chitwood, M.B., 1950. Introduction to Nematology.” University Park Press, Baltimore; Felix, M.A., Sternberg, P.W., 1996. Symmetry breakage in the development of one-armed gonads in nematodes. Development 122, 2129–2142). As such, comparative developmental biology of gonadogenesis offers the potential to investigate changes in developmental and cellular processes that result in novel organ morphologies and thus may give insights into how these changes can affect animal baupläne. Pristionchus pacificus is a free-living nematode that diverged from the model nematode Caenorhabditis elegans around 200–300 million years ago. The morphology and development of P. pacificus is highly homologous to that of C. elegans. However, many differences in morphology and the underlying molecular signaling networks are easy to identify, making P. pacificus ideal for a comparative approach. Here, we report a detailed description of the P. pacificus hermaphrodite gonad using electron and fluorescent microscopy that will provide a basis for both phenotypic studies of genetic mutations and in vivo molecular studies of cloned genes involved in P. pacificus gonad development. We report that the morphology of the P. pacificus gonad is distinct from that of C. elegans. Among these differences are germ line patterning differences, heterochronic differences, novel gonadal arm-migrations, novel cellular composition of some somatic tissues (e.g., the number of cells that comprise the sheath and different spermathecal regions are different), the absence of a somatic tissue (e.g., the spermathecal valve cells), a novel architecture for the sheath, and changes in the cellular and sub-cellular morphology of the individual sheath cells. Additionally, we report a set of cell ablations in P. pacificus that indicate extensive cell communication between the somatic gonadal tissues and the germ line. Individual ablation experiments in P. pacificus show significant differences in the effects of individual somatic tissues on germ line patterning in comparison to C. elegans.
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秀丽隐杆线虫生殖细胞分化的控制。
DOI：
10.1002/9780470514573.ch10
发表时间：
1994
期刊：
Ciba Foundation symposium
影响因子：
--
作者：
Ellis,RE;Kimble,J
通讯作者：
Kimble,J
影响因子：
2.7
作者：
A. Pepper;Te-Wen Lo;D. Killian;D. Hall;E. Hubbard
通讯作者：
A. Pepper;Te-Wen Lo;D. Killian;D. Hall;E. Hubbard
影响因子：
4.6
作者：
S. Crittenden;E. Troemel;T. C. Evans;J. Kimble
通讯作者：
S. Crittenden;E. Troemel;T. C. Evans;J. Kimble
影响因子：
3.3
作者：
T. Schedl;J. Kimble
通讯作者：
T. Schedl;J. Kimble
秀丽隐杆线虫进入减数分裂的遗传调控。
DOI：
10.1242/dev.125.10.1803
发表时间：
1998
期刊：
Development (Cambridge, England)
影响因子：
--
作者：
Kadyk,LC;Kimble,J
通讯作者：
Kimble,J