SARS-CoV-2 exposure in wild white-tailed deer (Odocoileus virginianus).
SARS-CoV-2 exposure in wild white-tailed deer (Odocoileus virginianus).
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DOI:
10.1073/pnas.2114828118
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发表时间:
2021-11-23
影响因子:
11.1
通讯作者:
Shriner SA
中科院分区:
文献类型:
--
作者:
Chandler JC;Bevins SN;Ellis JW;Linder TJ;Tell RM;Jenkins-Moore M;Root JJ;Lenoch JB;Robbe-Austerman S;DeLiberto TJ;Gidlewski T;Kim Torchetti M;Shriner SA
Widespread human SARS-CoV-2 infections combined with human–wildlife interactions create the potential for reverse zoonosis from humans to wildlife. We targeted white-tailed deer (Odocoileus virginianus) for serosurveillance based on evidence these deer have angiotensin-converting enzyme 2 receptors with high affinity for SARS-CoV-2, are permissive to infection, exhibit sustained viral shedding, can transmit to conspecifics, exhibit social behavior, and can be abundant near urban centers. We evaluated 624 prepandemic and postpandemic serum samples from wild deer from four US states for SARS-CoV-2 exposure. Antibodies were detected in 152 samples (40%) from 2021 using a surrogate virus neutralization test. A subset of samples tested with a SARS-CoV-2 virus neutralization test showed high concordance between tests. These data suggest white-tailed deer in the populations assessed have been exposed to SARS-CoV-2.
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影响因子:
11.8
作者:
Zhao S;Schuurman N;Li W;Wang C;Smit LAM;Broens EM;Wagenaar JA;van Kuppeveld FJM;Bosch BJ;Egberink H
通讯作者:
Egberink H
影响因子:
11.8
作者:
Shriner SA;Ellis JW;Root JJ;Roug A;Stopak SR;Wiscomb GW;Zierenberg JR;Ip HS;Torchetti MK;DeLiberto TJ
通讯作者:
DeLiberto TJ
影响因子:
9.4
作者:
TSUNEMITSU, H;ELKANAWATI, ZR;SAIF, LJ
通讯作者:
SAIF, LJ
影响因子:
11.8
作者:
Freuling CM;Breithaupt A;Müller T;Sehl J;Balkema-Buschmann A;Rissmann M;Klein A;Wylezich C;Höper D;Wernike K;Aebischer A;Hoffmann D;Friedrichs V;Dorhoi A;Groschup MH;Beer M;Mettenleiter TC
通讯作者:
Mettenleiter TC
影响因子:
4.9
作者:
Delahay RJ;de la Fuente J;Smith GC;Sharun K;Snary EL;Flores Girón L;Nziza J;Fooks AR;Brookes SM;Lean FZX;Breed AC;Gortazar C
通讯作者:
Gortazar C