Assessing the risks of SARS-CoV-2 in wildlife.

Assessing the risks of SARS-CoV-2 in wildlife.
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DOI:
10.1186/s42522-021-00039-6
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发表时间:
2021
期刊:
影响因子:
4.9
通讯作者:
Gortazar C
Gortazar C
中科院分区:
其他
文献类型:
--
作者:
Delahay RJ;de la Fuente J;Smith GC;Sharun K;Snary EL;Flores Girón L;Nziza J;Fooks AR;Brookes SM;Lean FZX;Breed AC;Gortazar C

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新型冠状病毒SARS-CoV-2可能来自野生动物,传播给人类,随后在地球仪迅速传播,对人类健康和全球经济造成严重影响。自大流行开始以来,已经发生了许多涉及伴侣、养殖和动物园动物的人畜传播病例,传播到自由生活的野生动物的证据有限。在野生动物中建立感染宿主将给人类感染控制带来重大挑战,并可能对野生动物的福利和保护状况构成威胁。我们讨论了潜在的暴露,前进的传播和持久性的SARS-CoV-2在最初选择的野生哺乳动物(蝙蝠,犬科动物,猫科动物,鼬科动物,类人猿,啮齿动物和鹿科动物)。动态风险评估和有针对性的监测是早期发现野生动物感染的重要工具,在这里,我们描述了一个框架,用于整理和综合新出现的信息,为野生动物中SARS-CoV-2的有针对性的监测提供信息。监测工作应与来自公共和兽医卫生倡议的信息相结合,以深入了解野生哺乳动物在SARS-CoV-2流行病学中的潜在作用。
The novel coronavirus SARS-CoV-2 likely emerged from a wildlife source with transmission to humans followed by rapid geographic spread throughout the globe and severe impacts on both human health and the global economy. Since the onset of the pandemic, there have been many instances of human-to-animal transmission involving companion, farmed and zoo animals, and limited evidence for spread into free-living wildlife. The establishment of reservoirs of infection in wild animals would create significant challenges to infection control in humans and could pose a threat to the welfare and conservation status of wildlife. We discuss the potential for exposure, onward transmission and persistence of SARS-CoV-2 in an initial selection of wild mammals (bats, canids, felids, mustelids, great apes, rodents and cervids). Dynamic risk assessment and targeted surveillance are important tools for the early detection of infection in wildlife, and here we describe a framework for collating and synthesising emerging information to inform targeted surveillance for SARS-CoV-2 in wildlife. Surveillance efforts should be integrated with information from public and veterinary health initiatives to provide insights into the potential role of wild mammals in the epidemiology of SARS-CoV-2.
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