Infection pattern, case fatality rate and spread of Lassa virus in Nigeria.
Infection pattern, case fatality rate and spread of Lassa virus in Nigeria.
复制标题
尼日利亚的感染模式，病例死亡率和LASSA病毒的扩散。
DOI：
10.1186/s12879-021-05837-x
复制
发表时间：
2021-02-05
影响因子：
3.7
通讯作者：
Oni JP
中科院分区：
文献类型：
--
作者：
Yaro CA;Kogi E;Opara KN;Batiha GE;Baty RS;Albrakati A;Altalbawy FMA;Etuh IU;Oni JP
拉沙热（LF）是尼日利亚一种引起公众关注的人畜共患传染病。在尼日利亚，该疾病的感染动力学尚不清楚。这项研究旨在描述2017年至2020年拉沙病毒（LASV）的感染模式、病死率和传播情况。从尼日利亚疾病控制中心获得2016年12月至2020年9月的每周LF流行病学数据。确诊病例和死亡人数是按月份和州计算的。进行描述性统计并计算病死率。在ArcMap 10.7上绘制了四年期间LF的分布和扩散图。2016年12月至2020年9月，尼日利亚共报告确诊病例2787例，死亡516例。2017年、2018年、2019年及2020年的确诊个案及死亡个案分别为298、528、796及1165宗，而死亡个案则分别为79、125、158及158宗。超过60%的病例报告发生在两个州，即江户州和翁多州。LF病例从2017年的19个州蔓延到2020年的32个州和联邦首都直辖区（FCT）。四年来，翁多州的LF死亡率最高（25.39%）。LF的病死率（CFR）在2017年最高（26.5%），2018年、2019年和2020年的病死率分别为23.7%、19.6%和13.4%。四年的感染高峰均在2月份。感染在11月旱季开始时增加，直到4月雨季来临时才下降。尼日利亚各州感染LASV的人数每年都在增加。有必要通过使用病媒控制、卫生教育和早期诊断等综合办法加强控制战略。在线版本包含补充材料，可通过10.1186/s12879-021-05837-x获得。
Lassa fever (LF) is a zoonotic infectious disease of public concern in Nigeria. The infection dynamics of the disease is not well elucidated in Nigeria. This study was carried out to describe the pattern of infection, case fatality rate and spread of lassa virus (LASV) from 2017 to 2020. Weekly epidemiological data on LF from December, 2016 to September, 2020 were obtained from Nigeria Centre for Disease Control. The number of confirmed cases and deaths were computed according to months and states. Descriptive statistics was performed and case fatality rate was calculated. Distribution and spread maps of LF over the four years period was performed on ArcMap 10.7. A total of 2787 confirmed cases and 516 deaths were reported in Nigeria from December, 2016 to September, 2020. Increase in number of cases and deaths were observed with 298, 528, 796 and 1165 confirmed cases and 79, 125, 158 and 158 deaths in 2017, 2018, 2019 and 2020 respectively. Over 60% of the cases were reported in two states, Edo and Ondo states. The LF cases spread from 19 states in 2017 to 32 states and Federal Capital Territory (FCT) in 2020. Ondo state (25.39%) had the highest of deaths rate from LF over the four years. Case fatality rate (CFR) of LF was highest in 2017 (26.5%) with CFR of 23.7, 19.6 and 13.4% in 2018, 2019 and 2020 respectively. The peak of infection was in the month of February for the four years. Infections increases at the onset of dry season in November and decline till April when the wet season sets-in. There is an annual increase in the number of LASV infection across the states in Nigeria. There is need to heighten control strategies through the use of integrated approach, ranging from vector control, health education and early diagnosis. The online version contains supplementary material available at 10.1186/s12879-021-05837-x.
登录
查看更多内容
影响因子：
4.6
作者：
Olayemi A;Cadar D;Magassouba N;Obadare A;Kourouma F;Oyeyiola A;Fasogbon S;Igbokwe J;Rieger T;Bockholt S;Jérôme H;Schmidt-Chanasit J;Garigliany M;Lorenzen S;Igbahenah F;Fichet JN;Ortsega D;Omilabu S;Günther S;Fichet-Calvet E
通讯作者：
Fichet-Calvet E
影响因子：
158.5
作者：
MCCORMICK, JB;KING, IJ;BELMONTWILLIAMS, R
通讯作者：
BELMONTWILLIAMS, R
DOI：
10.4269/ajtmh.1970.19.670
发表时间：
1970-01-01
影响因子：
3.3
作者：
FRAME, JD;BALDWIN, JM;TROUP, JM
通讯作者：
TROUP, JM
DOI：
10.1098/rstb.2001.0888
发表时间：
2001-07-29
影响因子：
6.3
作者：
Taylor, LH;Latham, SM;Woolhouse, MEJ
通讯作者：
Woolhouse, MEJ
影响因子：
11.8
作者：
Haas, WH;Breuer, T;Günther, S
通讯作者：
Günther, S