Recent developments in functional and structural imaging of aphasia recovery after stroke.
Recent developments in functional and structural imaging of aphasia recovery after stroke.
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DOI：
10.1080/02687038.2010.530672
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发表时间：
2011
期刊：
影响因子：
2
通讯作者：
Crosson B
中科院分区：
文献类型：
--
作者：
Meinzer M;Harnish S;Conway T;Crosson B
功能和结构神经影像学技术可以增加我们对脑卒中后语言障碍（失语症）恢复的神经过程的了解。在这篇综述中，我们重点介绍了失语症恢复的神经影像学研究的最新进展。我们回顾了（a）失语症局部脑功能和功能连接的横断面研究结果，（B）使用纵向（干预）范式的结构和功能成像结果，（c）由功能成像技术指导的新辅助治疗（例如，脑电刺激）和（d）与中风后语言恢复和治疗反应的预后有关的研究。数据采集和分析的最新发展促进了对中风后语言恢复的神经基础的更好理解和更现实的建模。此外，不同神经影像学方案的组合可以为自发和治疗诱导的恢复期间的神经可塑性脑重塑提供汇聚证据。研究人员也开始使用复杂的成像分析来提高预后的准确性，这可能最终通过更有效的治疗计划来改善患者护理。脑刺激技术提供了一种新的和令人兴奋的方式来提高中风后的恢复潜力。
Functional and structural neuroimaging techniques can increase our knowledge about the neural processes underlying recovery from post-stroke language impairments (aphasia). In the present review we highlight recent developments in neuroimaging research of aphasia recovery. We review (a) cross-sectional findings in aphasia with regard to local brain functions and functional connectivity, (b) structural and functional imaging findings using longitudinal (intervention) paradigms, (c) new adjunct treatments that are guided by functional imaging techniques (e.g., electrical brain stimulation) and (d) studies related to the prognosis of language recovery and treatment responsiveness after stroke. More recent developments in data acquisition and analysis foster better understanding and more realistic modelling of the neural substrates of language recovery after stroke. Moreover, the combination of different neuroimaging protocols can provide converging evidence for neuroplastic brain remodelling during spontaneous and treatment-induced recovery. Researchers are also beginning to use sophisticated imaging analyses to improve accuracy of prognosis, which may eventually improve patient care by allowing for more efficient treatment planning. Brain stimulation techniques offer a new and exciting way to improve the recovery potential after stroke.
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DOI：
10.1523/jneurosci.2227-10.2010
发表时间：
2010-09-01
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Fridriksson J
通讯作者：
Fridriksson J
影响因子：
5.7
作者：
Bonakdarpour, B.;Parrish, T. B.;Thompson, C. K.
通讯作者：
Thompson, C. K.
影响因子：
5.3
作者：
Adkins, DeAnna L.;Campos, Peter;Jones, Theresa A.
通讯作者：
Jones, Theresa A.
影响因子：
3.7
作者：
Fridriksson, Julius;Bonilha, Leonardo;Rorden, Chris
通讯作者：
Rorden, Chris
影响因子：
2.5
作者：
Abutalebi, Jubin;Della Rosa, Pasquale Anthony;Cappa, Stefano F.
通讯作者：
Cappa, Stefano F.