The type-VI secretion system of the beneficial symbiont Vibrio fischeri.

The type-VI secretion system of the beneficial symbiont Vibrio fischeri.
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DOI:
10.1099/mic.0.001302
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发表时间:
2023-02
期刊:
影响因子:
2.8
通讯作者:
Miyashiro, Tim I.
Miyashiro, Tim I.
中科院分区:
生物学4区
文献类型:
--
作者:
Guckes, Kirsten R.;Miyashiro, Tim I.

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夏威夷短尾乌贼Euprymna campaopes与海洋细菌之间的互惠共生 费氏弧菌 是一个强大的实验系统,用于确定细胞间相互作用如何影响动物-细菌协会。在自然界中,这种共生关系的特点是多种菌株, 费氏弧菌 在每只成年动物体内,这表明不同的菌株最初在每只鱿鱼中定居。各种研究表明,某些菌株 费氏弧菌 具有VI型分泌系统(T6 SS),可抑制其他菌株在同一宿主环境中建立共生关系。T6 SS是一种细菌近战武器,它使细胞能够通过柳叶刀样装置转移毒性效应物来杀死相邻细胞。本文综述了近年来对T6 SS结构和表达的调控因素的研究进展,包括T6 SS的表达、T6 费氏弧菌 以及它对共生关系的影响
The mutualistic symbiosis between the Hawaiian bobtail squid Euprymna scolopes and the marine bacterium Vibrio fischeri is a powerful experimental system for determining how intercellular interactions impact animal–bacterial associations. In nature, this symbiosis features multiple strains of V. fischeri within each adult animal, which indicates that different strains initially colonize each squid. Various studies have demonstrated that certain strains of V. fischeri possess a type-VI secretion system (T6SS), which can inhibit other strains from establishing symbiosis within the same host habitat. The T6SS is a bacterial melee weapon that enables a cell to kill adjacent cells by translocating toxic effectors via a lancet-like apparatus. This review describes the progress that has been made in understanding the factors that govern the structure and expression of the T6SS in V. fischeri and its effect on the symbiosis.
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