Use and perceived usefulness of a just-in-time resonance breathing intervention adjunct for substance use disorder: Contextual and physiological predictors.
Use and perceived usefulness of a just-in-time resonance breathing intervention adjunct for substance use disorder: Contextual and physiological predictors.
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针对物质使用障碍的即时共振呼吸干预辅助剂的使用和感知有用性：背景和生理预测因素。
DOI：
10.3389/fpsyt.2022.945751
复制
发表时间：
2022
影响因子：
4.7
通讯作者：
Buckman, Jennifer F.
中科院分区：
文献类型：
--
作者：
Price, Julianne L.;Bates, Marsha E.;Pawlak, Anthony P.;Uhouse, Sarah Grace;Todaro, Sabrina M.;Morgano, Julie;Buckman, Jennifer F.
关键词：
对酒精和其他药物的渴望通常被描述为一种短暂的过度觉醒状态，它会干扰一个人使用自上而下策略的能力。因此，最好是通过自下而上的调制“在此刻”中断。我们最近报告了通过移动的手机应用程序提供的间歇性共振起搏呼吸（eRPB），作为药物使用障碍（SUD）门诊治疗的附加治疗，在8周的干预过程中可有效抑制渴望（NCT#02579317）。然而，并非所有参与者都参与了eRPB应用程序，并且每周有用性评级的个体内和个体间差异很大。在这里，我们检查了基线人口统计学，生理学和精神病学指标以及随时间变化的积极，消极和诱惑渴望触发因素，作为eRPB应用程序使用频率和有用性评级的预测因素。77名门诊女性被随机分配到eRPB（0.1 Hz）或快节奏呼吸假（0.23 Hz）条件。在随机化前治疗入组的前3周内评估基线指标。在整个干预过程中，每周测量应用程序使用频率、有用性评级和触发暴露。将变量输入到具有向前逐步模型选择的边际均值模型中，并作为使用和有用性的预测因子进行检查。频繁使用应用程序与终生酒精使用障碍（AUD）诊断（p = 0.026），更高的有用性评级（p < 0.001）和更少的积极触发因素（例如，庆祝、社会化; p < 0.001）。在基线时，应用程序使用频率与心血管容量增加之间存在趋势水平相关性（p = 0.088）。较高的有用性评级与更多的负面触发因素（如，。孤独、沮丧; p < 0.001）和副交感神经失调（p = 0.05）。仅在eRPB组中存在应用程序使用频率和有用性评级之间的正相关关系（p = 0.045）。将理想的候选人和时刻与唤醒调节抗渴望干预相匹配，可以帮助简化eRPB在SUD治疗中的筛选和实施。https：//clinicaltrials.gov/ct2/show/NCT02579317，标识符NCT 02579317。
Craving for alcohol and other drugs is often described as a momentary hyperarousal state that interferes with one's ability to use top-down strategies. As such, it may be best interrupted ‘in the moment' through bottom-up modulation. We recently reported that episodic resonance paced breathing (eRPB) delivered via mobile phone app as an add-on to outpatient treatment for substance use disorder (SUD) was effective at dampening craving over the course of an 8-week intervention (NCT#02579317). However, not all participants engaged with the eRPB app and there was high intra- and inter-individual variability in weekly ratings of usefulness. Here we examined baseline demographic, physiological, and psychiatric measures as well as time-varying exposure to positive, negative, and temptation craving triggers as predictors of frequency of eRPB app use and ratings of usefulness. Seventy-seven outpatient women were randomized to an eRPB (0.1 Hz) or a faster paced breathing sham (0.23 Hz) condition. Baseline measures were assessed within the first 3 weeks of treatment entry prior to randomization. App use frequency, ratings of usefulness, and trigger exposure were measured weekly throughout the intervention. Variables were entered into marginal means models with forward stepwise model selection and examined as predictors of use and usefulness. Frequent app use was associated with a lifetime alcohol use disorder (AUD) diagnosis (p = 0.026), higher ratings of usefulness (p < 0.001), and fewer exposures to positive triggers (e.g., celebration, socialization; p < 0.001). There was a trend-level association between frequency of app use and greater cardiovascular capacity at baseline (p = 0.088). Higher ratings of usefulness were associated with greater exposure to negative triggers (e.g,. loneliness, frustration; p < 0.001) and parasympathetic dysregulation at baseline (p = 0.05). A positive relationship between app use frequency and ratings of usefulness was present only in the eRPB group (p = 0.045). Matching ideal candidates and moments to an arousal modulation anti-craving intervention can help streamline screening and implementation of eRPB in the treatment of SUD. https://clinicaltrials.gov/ct2/show/NCT02579317, identifier NCT02579317.
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影响因子：
3.4
作者：
Eddie D;Bates ME;Buckman JF
通讯作者：
Buckman JF
影响因子：
4.4
作者：
Alayan, Nour;Eddie, David;Carmody, Dennis P.
通讯作者：
Carmody, Dennis P.
影响因子：
7.6
作者：
Franklin, Teresa R.;wang, Ze;Childress, Anna Rose
通讯作者：
Childress, Anna Rose
DOI：
10.36518/2689-0216.1243
发表时间：
2022-01-01
期刊：
HCA healthcare journal of medicine
影响因子：
--
作者：
Calabrese, Jordan;Brown, Jonathan;Jo, Young
通讯作者：
Jo, Young
影响因子：
1.1
作者：
ElGeili, El Sheikh S.;Bashir, Taha Z.
通讯作者：
Bashir, Taha Z.