Intestinal cell proliferation is influenced by intakes of protein and energy, aflatoxin, and whole-body radiation.
Intestinal cell proliferation is influenced by intakes of protein and energy, aflatoxin, and whole-body radiation.
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肠细胞增殖受到蛋白质和能量摄入、黄曲霉毒素和全身辐射的影响。
DOI：
10.1080/01635589409514328
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发表时间：
1994
期刊：
影响因子：
--
通讯作者：
Ames,BN
中科院分区：
文献类型：
--
作者：
Fleming,SE;Youngman,LD;Ames,BN
通过对饲料蛋白质含量（5%、10%和20%酪蛋白饲料）、能量限制（能量摄取量为20%酪蛋白饲料摄取量的60%）、总摄取量（饲料摄取量为20%酪蛋白饲料摄取量的60%）、黄曲霉毒素和全身照射对年轻雄性F344大鼠肠道上皮细胞增殖的影响进行了测量。用[3H]胸腺嘧啶技术测定空肠、回肠、结肠近端和结肠远端切片的细胞增殖。将能量或总饮食摄入量限制在任意水平的40%，可减少整个肠道上皮细胞的增殖。与5%酪蛋白日粮相比，20%酪蛋白日粮导致所有肠段的细胞增殖均略有降低。辐射诱导空肠和回肠细胞增殖减少；20%的酪蛋白饮食可以防止这种下降。黄曲霉毒素b1预处理降低了整个肠道的肠细胞增殖，这种减少不受日粮蛋白质含量的影响。
Intestinal epithelial cell proliferation in young male F344 rats was measured in response to dietary protein content (5%, 10%, and 20% casein diets), energy restriction (energy intake was 60% of ad libitum energy intakes of animals consuming the 20% casein diet), total diet restriction (dietary intake was 60% of the ad libitum intake of 20% casein diet group), aflatoxin administration, and whole body irradiation. Cellular proliferation was measured in sections of jejunum, ileum, proximal colon, and distal colon with the [3H]thymidine technique. Restricting energy or total diet intakes by 40% from ad libitum levels reduced proliferation in epithelial cells throughout the intestine. In comparison to the 5% casein diet, the 20% casein diet resulted in modestly lower cellular proliferation in all intestinal segments. Radiation induced a decrease in cellular proliferation in the jejunum and ileum; this decrease was prevented by a 20% casein diet. Pretreatment with aflatoxin B1decreased intestinal cell proliferation throughout the intestine, and this decrease was not influenced by the protein content of the diet.
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影响因子：
11.2
作者：
K. Carroll
通讯作者：
K. Carroll
癌前病变的持续发展依赖于高蛋白质摄入。
DOI：
10.1080/01635589209514213
发表时间：
1992
期刊：
Nutrition and cancer
影响因子：
--
作者：
Youngman,LD;Campbell,TC
通讯作者：
Campbell,TC
影响因子：
11.2
作者：
S. Preston‐Martin;M. Pike;R. Ross;P. A. Jones;B. Henderson
通讯作者：
S. Preston‐Martin;M. Pike;R. Ross;P. A. Jones;B. Henderson
DOI：
10.1080/17450399009421084
发表时间：
1990-05-01
期刊：
ARCHIV FUR TIERERNAHRUNG-ARCHIVES OF ANIMAL NUTRITION
影响因子：
--
作者：
ABDELHAMID, AM;ELSHAWAF, I;GAMIL, T
通讯作者：
GAMIL, T
DOI：
10.1093/geronj/37.2.130
发表时间：
1982-01-01
期刊：
JOURNALS OF GERONTOLOGY
影响因子：
--
作者：
YU, BP;MASORO, EJ;LYND, FT
通讯作者：
LYND, FT