The supplementation of a prebiotic improves the microbial community in the gut and the skin of Atlantic salmon (Salmo salar).
The supplementation of a prebiotic improves the microbial community in the gut and the skin of Atlantic salmon (Salmo salar).
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DOI：
10.1016/j.aqrep.2022.101204
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发表时间：
2022-08
影响因子：
3.7
通讯作者：
中科院分区：
文献类型：
--
作者：
水产养殖业的增长受到越来越多挑战的阻碍，主要是传染病和不适当或不可持续的鱼类营养。因此，至关重要的是制定新的预防战略，将传染病和药物干预降至最低。通过管理鱼类的微生物群落，可以改善鱼类的营养挑战和健康。微生物群可以通过为宿主代谢大部分不可消化的饲料成分或合成必要的微量营养素，在鱼类生理中发挥关键作用，特别是在消化方面。除了营养作用外，微生物群被认为是抵御病原体的第一道防线。本研究将1，3/1，6-β-葡聚糖、甘露寡糖、核酸、核苷酸、中链脂肪酸和单链脂肪酸组成的新型益生素混合物(Selectovit)在不同包裹量(0.0；0.5；1.0；2.0 g/kg)的条件下对大西洋鲑鱼(Salmo Salar)进行了试验。通过实验饲料试验和16个月的S rRNA微生物群分析，评估了益生素混合物对鱼类生长以及胃肠道和皮肤内微生物群落的影响。总体而言，补充剂对增长没有显著影响。然而，我们清楚地证明，益生元可以显著操纵远端肠道和皮肤的微生物群落。几种潜在的有益细菌，如芽孢杆菌和支原体。与对照组相比，益生菌饲养组的细菌数量显著增加。相比之下，在喂食益生菌混合物的鲑鱼中，假定的致病细菌数量较少。有趣的是，补充剂在皮肤上引起的变化比在肠道中引起的更多。越来越多的证据表明，鱼类消化系统的微生物群落和外粘膜之间以及与宿主免疫系统之间存在高度复杂的相互作用。这一领域的进一步研究可能导致创造新的细菌生物标记物和用于鱼类消化健康监测的新的非侵入性策略。改善鱼类肠道中的粘膜健康和共生微生物群落。益生菌影响包括皮肤在内的非目标组织--这是一种抵御病原体的屏障。使用16个S的rRNA图谱，我们展示了对有益细菌分类群的积极影响。益生素添加剂减少了肠道和皮肤中假定的致病属的丰度。大西洋鲑鱼皮肤微生物群与食性之间的强相互作用。
Aquaculture growth is hindered by an increasing number of challenges, primarily infectious diseases and inappropriate or unsustainable fish nutrition. Hence it is critical to develop novel prevention strategies to minimise infectious diseases and pharmaceutical interventions. Nutritional challenges and the health of the fish could be improved by managing their microbial communities. Microbiomes can play a crucial role in fish physiology, particularly in digestion, by metabolizing largely indigestible feed components for the host or synthesis essential micronutrients. Beyond their nutritional role, microbiomes are considered the first line of defence against pathogens. In this study, a novel prebiotic mix (Selectovit), composed of 1,3/1,6-beta glucans, mannan-oligosaccharides, nucleic acids, nucleotides, medium chain fatty acids and single chain fatty acids, was tested at different inclusion levels (0.0; 0.5; 1.0; 2.0 g/kg) in the diet of Atlantic salmon (Salmo salar). Using experimental feed trials and 16 S rRNA microbiome profiling, the impact of the prebiotic blend on fish growth and microbial community within both the gastrointestinal tract and the skin was assessed. Overall, the supplement showed no significant impact on growth. However, we clearly demonstrate that the prebiotic can significantly manipulate the microbial community of the distal intestine and the skin. Several potential beneficial bacteria such as Bacillus and Mycoplasma spp. were significantly more abundant in the prebiotic-fed groups compared to the control. In contrast, putative pathogenic bacteria were less abundant in the salmon fed the prebiotic blend. Interestingly, the supplement induced more changes in the skin than in the gut. There is growing evidence in fish for highly complex interactions between the microbial communities of the digestive system and external mucosa, and with the host immune system. Further research in this field could lead to the creation of novel bacterial biomarkers and new non-invasive strategies for fish digestive health monitoring. Improving mucosal health and commensal microbial communities in the intestine of fish. Prebiotics influence non-target tissues including the skin – a barrier to pathogens. Using 16 S rRNA profiling, we demonstrate positive effects on beneficial bacterial taxa. Prebiotic additive reduced abundance of putative pathogenic genera in the gut and skin. Strong interaction between the skin microbiome and the diet of Atlantic Salmon.
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影响因子：
4.7
作者：
Adams, Alexandra
通讯作者：
Adams, Alexandra
影响因子：
4.5
作者：
Burrells, C;Williams, PD;Forno, PF
通讯作者：
Forno, PF
影响因子：
7.7
作者：
Bohmann, Kristine;Elbrecht, Vasco;Caroe, Christian;Bista, Iliana;Leese, Florian;Bunce, Michael;Yu, Douglas W.;Seymour, Mathew;Dumbrell, Alex J.;Creer, Simon
通讯作者：
Creer, Simon
影响因子：
5.2
作者：
Egerton S;Culloty S;Whooley J;Stanton C;Ross RP
通讯作者：
Ross RP
影响因子：
4.4
作者：
Dailey, Frank E.;McGraw, Joseph E.;Munro, James B.
通讯作者：
Munro, James B.