Associations between mental disorders and subsequent onset of hypertension.
Associations between mental disorders and subsequent onset of hypertension.
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DOI：
10.1016/j.genhosppsych.2013.11.002
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发表时间：
2014-03
影响因子：
7
通讯作者：
Scott KM
中科院分区：
文献类型：
--
作者：
Stein DJ;Aguilar-Gaxiola S;Alonso J;Bruffaerts R;de Jonge P;Liu Z;Miguel Caldas-de-Almeida J;O'Neill S;Viana MC;Al-Hamzawi AO;Angermeyer MC;Benjet C;de Graaf R;Ferry F;Kovess-Masfety V;Levinson D;de Girolamo G;Florescu S;Hu C;Kawakami N;Maria Haro J;Piazza M;Posada-Villa J;Wojtyniak BJ;Xavier M;Lim CC;Kessler RC;Scott KM
先前的研究表明，各种心理症状（如抑郁、焦虑、愤怒、酗酒）与高血压之间存在显著关联。然而，常见精神障碍与随后的成年高血压发病之间的关联的存在和程度仍不清楚。此外，关于这种关联如何因性别或生命历程而变化的数据很少。数据来自世界精神卫生调查（包括19个国家，52,095名成年人）。生存分析估计了首次发病的常见精神障碍和随后发病的高血压之间的关联，有无精神合并症调整。研究了性别和精神障碍和高血压发病的生命历程阶段的关联强度的变化。经精神病学共病调整后，抑郁、惊恐障碍、社交恐惧症、特定恐惧症、暴食症、神经性贪食症、酗酒和药物滥用与随后的高血压诊断显著相关（or范围为1.1 - 1.6）。终生精神障碍的数量与随后的高血压呈剂量-反应关系。在社交恐惧症和酗酒方面，男性与高血压的关联比女性更强。对于惊恐障碍，其与高血压的关联在早发性高血压中尤为明显。抑郁、焦虑、冲动饮食障碍和物质使用障碍与随后的高血压诊断显著相关。这些数据强调了早期发现精神障碍以及对患有这些疾病的人进行身体健康监测的重要性。
Previous work has suggested significant associations between various psychological symptoms (e.g. depression, anxiety, anger, alcohol abuse) and hypertension. However, the presence and extent of associations between common mental disorders and subsequent adult onset of hypertension remains unclear. Further, there is little data available on how such associations vary by gender or over life course. Data from the World Mental Health Surveys (comprising 19 countries, and 52,095 adults) were used. Survival analyses estimated associations between first onset of common mental disorders and subsequent onset of hypertension, with and without psychiatric comorbidity adjustment. Variations in the strength of associations by gender and by life course stage of onset of both the mental disorder and hypertension were investigated. After psychiatric comorbidity adjustment, depression, panic disorder, social phobia, specific phobia, binge eating disorder, bulimia nervosa, alcohol abuse, and drug abuse were significantly associated with subsequent diagnosis of hypertension (with ORs ranging from 1.1 to 1.6). Number of lifetime mental disorders was associated with subsequent hypertension in a dose-response fashion. For social phobia and alcohol abuse, associations with hypertension were stronger for males than females. For panic disorder, the association with hypertension was particularly apparent in earlier onset hypertension. Depression, anxiety, impulsive eating disorders, and substance use disorders disorders were significantly associated with the subsequent diagnosis of hypertension. These data underscore the importance of early detection of mental disorders, and of physical health monitoring in people with these conditions..
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影响因子：
4.4
作者：
Geleijnse, JM;Kok, FJ;Grobbee, DE
通讯作者：
Grobbee, DE
影响因子：
5.8
作者：
Greenage, Michael;Kulaksizoglu, Burak;Ali, Rizwan
通讯作者：
Ali, Rizwan
影响因子：
8.2
作者：
Korte, SM;Koolhaas, JM;McEwen, BS
通讯作者：
McEwen, BS
DOI：
10.1111/j.1524-6175.2006.05126.x
发表时间：
2006-11-01
期刊：
Journal of clinical hypertension (Greenwich, Conn.)
影响因子：
--
作者：
Pickering, Thomas G
通讯作者：
Pickering, Thomas G
影响因子：
4.2
作者：
SULS, J;WAN, CK;COSTA, PT
通讯作者：
COSTA, PT