Microplastics increase mercury bioconcentration in gills and bioaccumulation in the liver, and cause oxidative stress and damage in Dicentrarchus labrax juveniles.
Microplastics increase mercury bioconcentration in gills and bioaccumulation in the liver, and cause oxidative stress and damage in Dicentrarchus labrax juveniles.
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DOI：
10.1038/s41598-018-34125-z
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发表时间：
2018-10-23
影响因子：
4.6
通讯作者：
Guilhermino L
中科院分区：
文献类型：
--
作者：
Barboza LGA;Vieira LR;Branco V;Carvalho C;Guilhermino L
海洋环境中存在的微塑料和其他几种污染物越来越令人担忧。然而，关于含有微塑料和其他污染物的混合物对海洋物种的毒性的知识仍然很少。本研究的主要目的是研究汞（0.010和0.016 mg/L）、微塑料（0.26和0.69 mg/L）以及两种物质的混合物（相同浓度，全因子）暴露96 h后，在鳃和肝脏中可能引起的氧化应激和脂质氧化损伤。实验结果表明，微塑料可能会对拉布拉多幼鱼的汞生物富集（鳃）和汞生物累积（肝脏）产生影响。结果表明，水体中微塑料的存在增加了鳃和肝脏中汞的含量。拉布拉多幼鱼微塑料和汞，单独或混合，导致两个器官的氧化应激。基于抗氧化酶活性的总诱导，暴露于含有最低浓度的两种物质的混合物的鱼的毒理学相互作用的类型是在鳃中的添加，和在肝脏中的添加或协同作用。这些结果强调需要进一步解决微塑料在不同物种中的生物浓缩，生物累积和其他环境污染物的毒性中的作用。
The presence of microplastics and several other pollutants in the marine environment is of growing concern. However, the knowledge on the toxicity of mixtures containing microplastics and other contaminants to marine species is still scarce. The main goals of this study were to investigate the oxidative stress and lipid oxidative damage potentially induced by 96 h of exposure to mercury (0.010 and 0.016 mg/L), microplastics (0.26 and 0.69 mg/L), and mixtures of the two substances (same concentrations, full factorial) in the gills and liver of D. labrax juveniles, and the possible influence of microplastics on mercury bioconcentration (gills) and bioaccumulation (liver). The results indicate that the presence of microplastics in the water increased the concentration of mercury in gills and liver of D. labrax juveniles. Microplastics and mercury, alone and in mixtures, caused oxidative stress in both organs. Based on the total induction of antioxidant enzymatic activity, the type of toxicological interaction in fish exposed to the mixture containing the lowest concentration of the two substances was addition in gills, and addition or synergism in the liver. These results stress the need to further address the role of microplastics in the bioconcentration, bioaccumulation, and toxicity of other environmental contaminants in different species.
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影响因子：
8.9
作者：
de Sa, Luis Carlos;Luis, Luis G.;Guilhermino, Lucia
通讯作者：
Guilhermino, Lucia
影响因子：
4.5
作者：
Ferreira, Pedro;Fonte, Elsa;Guilhermino, Lucia
通讯作者：
Guilhermino, Lucia
DOI：
10.1007/s11270-015-2735-5
发表时间：
2016
期刊：
Water, air, and soil pollution
影响因子：
--
作者：
Bełdowska M;Falkowska L
通讯作者：
Falkowska L
影响因子：
5.9
作者：
Duis K;Coors A
通讯作者：
Coors A
影响因子：
5.8
作者：
Abayomi, Oyebamiji Abib;Range, Pedro;Ben-Hamadou, Radhouane
通讯作者：
Ben-Hamadou, Radhouane