Seroprevalence of CMV IgG and IgM in Korean women of childbearing age.

Seroprevalence of CMV IgG and IgM in Korean women of childbearing age.
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DOI:
10.1002/jcla.23716
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发表时间:
2021-04
影响因子:
2.7
通讯作者:
Lee EH
Lee EH
中科院分区:
医学4区
文献类型:
--
作者:
Choi R;Lee S;Lee SG;Lee EH

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本研究的目的是通过测定韩国育龄妇女巨细胞病毒IgG和IgM抗体的血清学状况,探讨巨细胞病毒(CMV)感染的血清患病率。我们回顾性回顾了2009年1月至2019年12月期间接受CMV IgG和IgM检测的15-49岁韩国女性的检测结果。观察CMV IgG和IgM血清按年龄和年龄的流行情况。研究时间为11年,6837份样本中,95.8%的CMV igg阳性。15 - <20岁的女性血清阳性率明显低于年龄较大的人群(77.5%)。在6837例CMV IgG检测中,75.9%(5186例)同时检测CMV IgM,其中2.4%为IgM阳性。考虑到20岁以下妇女的巨细胞病毒血清阳性率较低,她们可能需要进行巨细胞病毒感染的产前教育。
The aim of this study was to investigate the seroprevalence of cytomegalovirus (CMV) infection using the serologic status of CMV IgG and IgM antibodies in Korean women of childbearing age. We retrospectively reviewed CMV IgG and IgM test results from Korean women aged 15–49 years who underwent testing between January 2009 and December 2019. Seroprevalence of CMV IgG and IgM by year and age was investigated. The study period was 11 years, and among 6837 samples tested, 95.8% were CMV IgG–positive. The seropositivity in women aged 15‐ <20 years was significantly lower (77.5%) than older age groups. Among 6837 total CMV IgG tests, 75.9% (5186) had concurrently measured CMV IgM results among which 2.4% were IgM‐positive. Considering the low CMV seropositivity of women younger than 20 years, they may need prenatal education for CMV infection.
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