Caregiver depression is associated with hair cortisol in a low-income sample of preschool-aged children.
Caregiver depression is associated with hair cortisol in a low-income sample of preschool-aged children.
复制标题
DOI：
10.1016/j.psyneuen.2020.104675
复制
发表时间：
2020-07
影响因子：
3.7
通讯作者：
Brentani A
中科院分区：
文献类型：
--
作者：
Liu CH;Fink G;Brentani H;Brentani A
照顾者的抑郁和儿童的气质特征（例如努力控制）与儿童下丘脑-垂体-肾上腺（HPA）轴的失调有关。头发皮质醇浓度 (HCC) 已越来越多地被采用作为 HPA 轴活动的综合标志物。本研究以高风险、低收入学龄前儿童为样本，探讨了看护者抑郁症状、看护者社会支持、儿童努力控制和儿童 HCC 之间的关联。 154 名护理人员主要由母亲及其孩子（2 至 5 岁）组成，他们参加了在巴西圣保罗贫困城市社区进行的出生队列研究。通过在家中进行个人访谈，看护者对他们的社会心理经历和孩子的行为进行了评分。头发长度至少为 3 厘米的儿童的头发样本。在多变量回归分析中，未经调整的模型显示儿童年龄与 HCC 呈负相关（β = -0.32，p <.001）。考虑了儿童年龄和性别的调整模型显示，看护者抑郁症状与 HCC 之间呈正相关（β = 0.22，p < .01）。看护者的社会支持和儿童的努力控制与 HCC 无关。照顾者报告抑郁风险较高的儿童中 HCC 升高与先前的研究结果一致，即暴露于持续压力的儿童中 HCC 升高。鉴于 HCC 与年龄之间的负相关，儿童 HCC 的稳定可能发生在学龄前儿童中。需要进行更多研究来确定照护者社会支持和努力控制的影响是否可以通过 HCC 体现出来。
Caregiver depression and child temperamental characteristics such as effortful control have been associated with child dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis. Hair cortisol concentrations (HCC) has been increasingly adopted as an integrated marker of HPA axis activity. This study examined the associations between caregiver depressive symptoms, caregiver social support, child effortful control, and child HCC in a sample of a high-risk, low-income preschool-aged children. 154 caregivers comprised mostly of mothers and their children (2-to-5 years) who were enrolled in a birth cohort study conducted in poor urban neighborhoods of São Paulo, Brazil. Through personal interviews at their homes, caregivers provided ratings of their psychosocial experiences and of their child’s behavior. Hair was sampled from children with at least a 3-cm hair length. In a multivariable regression analysis, an unadjusted model showed child age to be negatively associated with HCC (β = −0.32, p <.001). The adjusted model, which accounted for child age and sex, showed a positive relationship between caregiver depressive symptoms and HCC (β = 0.22, p < .01). Caregiver social support and child effortful control were not associated with HCC. The elevated HCC among children with caregivers reporting greater depression risk is consistent with prior findings showing elevated HCC among children exposed to persistent stress. Stabilization of child HCC may be occurring within preschool children given the negative association between HCC and age. Greater research is needed to determine whether the effects of caregiver social support and effortful control can be captured through HCC.
登录
查看更多内容
影响因子：
2.2
作者：
Liu, Cindy H.;Doan, Stacey N.
通讯作者：
Doan, Stacey N.
影响因子：
2.2
作者：
Flom M;St John AM;Meyer JS;Tarullo AR
通讯作者：
Tarullo AR
影响因子：
5
作者：
Kramer, Michael S.;Lydon, John;Platt, Robert W.
通讯作者：
Platt, Robert W.
DOI：
10.1590/s0102-311x2007001100005
发表时间：
2007-11-01
期刊：
Cadernos de Saúde Pública
影响因子：
--
作者：
Santos, Iná S.;Matijasevich, Alicia;Barros, Fernando C.
通讯作者：
Barros, Fernando C.
DOI：
10.3109/10253890.2013.817553
发表时间：
2013-11-01
影响因子：
2.3
作者：
Groeneveld, Marleen G.;Vermeer, Harriet J.;van IJzendoorn, Marinus H.
通讯作者：
van IJzendoorn, Marinus H.