Shear-Wave Elastography Assessments of Quadriceps Stiffness Changes prior to, during and after Prolonged Exercise: A Longitudinal Study during an Extreme Mountain Ultra-Marathon.
Shear-Wave Elastography Assessments of Quadriceps Stiffness Changes prior to, during and after Prolonged Exercise: A Longitudinal Study during an Extreme Mountain Ultra-Marathon.
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DOI：
10.1371/journal.pone.0161855
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发表时间：
2016
期刊：
影响因子：
3.7
通讯作者：
Croisille P
中科院分区：
文献类型：
--
作者：
Andonian P;Viallon M;Le Goff C;de Bourguignon C;Tourel C;Morel J;Giardini G;Gergelé L;Millet GP;Croisille P
在运动医学中，人们对量化骨骼肌的弹性特性越来越感兴趣，特别是在极度肌肉刺激时，以提高我们对骨骼肌僵硬度改变对疼痛或损伤的影响的理解，以及这些参数之间关系的潜在机制。我们的主要目的是确定实时剪切波弹性成像（SWE）是否可以监测极限山地超级马拉松期间股四头肌弹性的变化，这是一种强大的机械应力模型。我们的研究涉及50名志愿者参加极限山地马拉松（距离：330公里，海拔：+ 24000米）。定量SWE速度和剪切模量测量在以下4个时间点进行：比赛前，比赛中途，比赛结束后和恢复后（+48小时）。同时还测量了血液生物标志物水平。与基线值（3.56±0.63 kPa）相比，在比赛结束后观察到股四头肌剪切模量显著下降（3.31±0.61 kPa） （p<0.001），随后在比赛后48小时，所有肌头以及以下三个肌头(股直肌（p = 0.003），股内侧肌（p = 0.033）和股外侧肌（p = 0.001）部分恢复（3.45±0.6 kPa）。我们的研究首次评估了在非侵入性SWE剪切模量测量的基础上，在长时间极限体力耐力运动中肌肉僵硬度的变化。我们的结论是，僵硬度的降低可能是由于四头肌在极端距离和独特海拔引起的超生理应激环境下过度使用造成的，这可能是炎症和肌肉肿胀的原因。因此，SWE可能是一种很有前途的工具，用于监测肌肉僵硬的生理或病理变化，并可能用于诊断和监测肌肉变化。
In sports medicine, there is increasing interest in quantifying the elastic properties of skeletal muscle, especially during extreme muscular stimulation, to improve our understanding of the impact of alterations in skeletal muscle stiffness on resulting pain or injuries, as well as the mechanisms underlying the relationships between these parameters. Our main objective was to determine whether real-time shear-wave elastography (SWE) can monitor changes in quadriceps muscle elasticity during an extreme mountain ultra-marathon, a powerful mechanical stress model. Our study involved 50 volunteers participating in an extreme mountain marathon (distance: 330 km, elevation: +24,000 m). Quantitative SWE velocity and shear modulus measurements were performed in most superficial quadriceps muscle heads at the following 4 time points: before the race, halfway through the race, upon finishing the race and after recovery (+48 h). Blood biomarker levels were also measured. A significant decrease in the quadriceps shear modulus was observed upon finishing the race (3.31±0.61 kPa) (p<0.001) compared to baseline (3.56±0.63 kPa), followed by a partial recovery +48 h after the race (3.45±0.6 kPa) (p = 0.002) across all muscle heads, as well as for each of the following three muscle heads: the rectus femoris (p = 0.003), the vastus medialis (p = 0.033) and the vastus lateralis (p = 0.001). Our study is the first to assess changes in muscle stiffness during prolonged extreme physical endurance exercises based on shear modulus measurements using non-invasive SWE. We concluded that decreases in stiffness, which may have resulted from quadriceps overuse in the setting of supra-physiological stress caused by the extreme distance and unique elevation of the race, may have been responsible for the development of inflammation and muscle swelling. SWE may hence represent a promising tool for monitoring physiologic or pathological variations in muscle stiffness and may be useful for diagnosing and monitoring muscle changes.
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影响因子：
3.3
作者：
DAVIES, CTM;THOMPSON, MW
通讯作者：
THOMPSON, MW
影响因子：
2.4
作者：
Gennisson, J. -L.;Renier, M.;Fink, M.
通讯作者：
Fink, M.
DOI：
10.1097/01.phm.0000029772.45258.43
发表时间：
2002-11-01
影响因子：
3
作者：
Clarkson, PM;Hubal, MJ
通讯作者：
Hubal, MJ
影响因子：
14.5
作者：
DIETZ, V;QUINTERN, J;BERGER, W
通讯作者：
BERGER, W
影响因子：
4.1
作者：
Fulford, J.;Eston, R. G.;Davies, R. C.
通讯作者：
Davies, R. C.