Arginine vasopressin: Direct and indirect action on metabolism.
Arginine vasopressin: Direct and indirect action on metabolism.
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DOI：
10.1016/j.peptides.2021.170555
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发表时间：
2021-08
期刊：
影响因子：
3
通讯作者：
Ueta Y
中科院分区：
文献类型：
--
作者：
Yoshimura M;Conway-Campbell B;Ueta Y
综述了AVP在代谢中的作用。简要概述了目前的知识有关AVP如何控制能量平衡和摄食行为。我们集中在生理方面，包括AVP，昼夜节律和糖皮质激素之间的关系。精氨酸加压素（arginine vasopressin，AVP）自1954年被发现以来，不仅因其具有收缩血管、重吸收肾脏水等外周功能，而且因其中枢作用而受到广泛关注。由于现在有相当多的证据表明AVP在摄食行为和能量平衡中起着至关重要的作用，因此它已成为治疗肥胖或其他肥胖相关代谢紊乱的有希望的治疗靶点。然而，AVP调节这些中枢过程的潜在机制仍然在很大程度上未知。在这篇综述中，我们将提供一个简短的概述，目前的知识有关AVP如何控制能量平衡和摄食行为，侧重于生理方面，包括AVP，昼夜节律和糖皮质激素之间的关系。
The roles of AVP on metabolism are described. A brief overview of the current knowledge concerning how AVP controls energy balance and feeding behavior is provided. We focused on physiological aspects including the relationship between AVP, circadian rhythmicity, and glucocorticoids. From its identification and isolation in 1954, arginine vasopressin (AVP) has attracted attention, not only for its peripheral functions such as vasoconstriction and reabsorption of water from kidney, but also for its central effects. As there is now considerable evidence that AVP plays a crucial role in feeding behavior and energy balance, it has become a promising therapeutic target for treating obesity or other obesity-related metabolic disorders. However, the underlying mechanisms for AVP regulation of these central processes still remain largely unknown. In this review, we will provide a brief overview of the current knowledge concerning how AVP controls energy balance and feeding behavior, focusing on physiological aspects including the relationship between AVP, circadian rhythmicity, and glucocorticoids.
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DOI：
10.1016/s1357-2725(00)00037-6
发表时间：
2000-09-01
影响因子：
4
作者：
Brostrom, MA;Reilly, BA;Bostrom, CO
通讯作者：
Bostrom, CO
影响因子：
4.1
作者：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
VANITALLIE, TB
影响因子：
16.2
作者：
Bielsky, IF;Hu, SB;Young, LJ
通讯作者：
Young, LJ
影响因子：
4.1
作者：
BUXTON, DB;FISHER, RA;OLSON, MS
通讯作者：
OLSON, MS