Reproducibility of Optic Nerve Head Measurements Obtained by Optical Coherence Tomography
Reproducibility of Optic Nerve Head Measurements Obtained by Optical Coherence Tomography
复制标题
通过光学相干断层扫描获得的视神经头测量的再现性
DOI：
10.1177/112067210501500412
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发表时间：
2005
影响因子：
1.7
通讯作者：
I. Fernández
中科院分区：
文献类型：
--
作者：
M. Olmedo;C. Cadarso;F. Gómez;C. Val;I. Fernández
目的评价光学相干断层扫描（Optical Coherence Tomography，OCT）对正常眼和青光眼患者视神经乳头（optic nerve head，ONH）形态测量的重复性。方法前瞻性仪器评价研究。在眼科诊所的两次访问期间进行的八次扫描中获得20只眼睛的ONH测量值（10名正常患者，10名青光眼患者，每个受试者一只眼睛）。在每只眼睛的八个疗程中的每一个疗程中，获得八个ONH形态测量学变量的估计值（参见主要结果测量）。前两次会议由两名操作员进行，然后休息30分钟。这些操作员随后完成了第三次和第四次会议。在第二次访视时重复该序列。通过使用成分方差模型计算这八个变量的期内、期间、访视间和术中再现性。组内相关系数（ICC）用于评估可靠性。结果垂直积分边缘面积、水平积分边缘面积、盘面积、杯面积、边缘面积、杯盘面积比、杯盘水平比、杯盘垂直比。除正常人水平积分边缘面积和边缘面积外，因子主题是所有变量的最重要方差来源。正常眼ICC测量的可靠性值均在81%以上，水平积分边缘面积（23.1%），边缘面积（33.3%）和视盘面积（64.7%）的测量除外。对于青光眼眼，除视盘面积（68.1%）外，所有值均高于85%。结论使用Zeiss 3000 OCT系统的快速光盘协议获得的ONH测量结果具有良好的重复性，对于正常和青光眼眼。
Purpose To evaluate reproducibility of optic nerve head (ONH) morphometry measurements obtained by optical coherence tomography (the fast optical disk protocol of the Zeiss model 3000 OCT system) in normal and glaucomatous eyes. Methods Prospective instrument-evaluation study. ONH measurements for 20 eyes were obtained in eight scan sessions taken during two visits to an ophthalmology clinic (10 normal patients, 10 glaucoma patients, one eye per subject). At every one of the eight sessions for each eye, estimates of eight ONH morphometry variables (see Main outcome measures) were obtained. The first two sessions were performed by two operators, followed by a 30-minute break. The same operators then completed a third and fourth session. This sequence was duplicated on a second visit. Intrasession, intersession, intervisit, and interoperator reproducibility of the eight variables were calculated by the use of a components variance model. Intraclass correlation coefficients (ICC) were used to assess reliability. Results Vertical integrated rim area, horizontal integrated rim area, disk area, cup area, rim area, cup/disk area ratio, cup/disk horizontal ratio, cup/disk vertical ratio. With the exception of the horizontal integrated rim area and rim area in normal subjects, the factor subject was the most important source of variance for all variables. Reliability values as measured by ICC for normal eyes were above 81%, with the exception of measurements of the horizontal integrated rim area (23.1%), rim area (33.3%), and disk area (64.7%). For glaucomatous eyes all values were above 85%, with the exception of the disk area (68.1%). Conclusions ONH measurements obtained using the fast optical disk protocol of the Zeiss 3000 OCT system show good reproducibility, for both normal and glaucomatous eyes.
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影响因子：
--
作者：
C. Bowd;R. Weinreb;Julia M. Williams;L. Zangwill
通讯作者：
C. Bowd;R. Weinreb;Julia M. Williams;L. Zangwill
影响因子：
4.2
作者：
Schuman, JS;Wollstein, G;Paunescu, LA
通讯作者：
Paunescu, LA
影响因子：
--
作者：
SCHUMAN, JS;HEE, MR;FUJIMOTO, JG
通讯作者：
FUJIMOTO, JG
影响因子：
--
作者：
HEE, MR;IZATT, JA;FUJIMOTO, JG
通讯作者：
FUJIMOTO, JG