Putative effects of endocrine disrupters on pubertal development in the human.
Putative effects of endocrine disrupters on pubertal development in the human.
复制标题
内分泌干扰物对人类青春期发育的假定影响。
DOI:
10.1053/beem.2002.0184
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发表时间:
2002
期刊:
影响因子:
--
通讯作者:
J. Toppari
中科院分区:
文献类型:
--
作者:
G. Teilmann;A. Juul;N. Skakkebaek;J. Toppari
Pubertal development is regulated by gonadotrophins and sex hormones. There has been a clear secular trend in the timing of puberty during the last century, puberty becoming earlier. Although improved nutrition is assumed to be the cause, this could partly be associated with exposure to so-called endocrine disrupters. Precocious puberty has been described in several case reports of accidental exposure to oestrogenic compounds in cosmetic products, food and pharmaceuticals. Local epidemics of premature thelarche have also been suggested to be linked to endocrine disrupters. Children adopted from developing countries to industrialized countries often develop precocious puberty. Not only precocious puberty, but also delayed puberty can, theoretically, be associated with exposure to endocrine disrupters. While it is very plausible that endocrine disrupters may disturb pubertal development, there is very little research on this and, therefore, we do not yet have any clear cause-effect relationships in humans.
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影响因子:
5
作者:
Berkey, CS;Gardner, JD;Colditz, GA
通讯作者:
Colditz, GA
影响因子:
10.4
作者:
Colón I;Caro D;Bourdony CJ;Rosario O
通讯作者:
Rosario O
影响因子:
5.1
作者:
Gladen, BC;Ragan, NB;Rogan, WJ
通讯作者:
Rogan, WJ
DOI:
10.1016/s0022-3476(05)82891-4
发表时间:
1990
期刊:
The Journal of pediatrics
影响因子:
--
作者:
VanWinter,JT;Noller,KL;Zimmerman,D;Melton3rd,LJ
通讯作者:
Melton3rd,LJ
影响因子:
5
作者:
Horn-Ross, PL;John, EM;Perez-Stable, EJ
通讯作者:
Perez-Stable, EJ