Innate Pulmonary Phagocytes and Their Interactions with Pathogenic Cryptococcus Species.
Innate Pulmonary Phagocytes and Their Interactions with Pathogenic Cryptococcus Species.
复制标题
DOI:
10.3390/jof9060617
复制
发表时间:
2023-05-27
期刊:
影响因子:
--
通讯作者:
中科院分区:
文献类型:
--
作者:
Cryptococcus neoformans is an opportunistic fungal pathogen that causes over 180,000 annual deaths in HIV/AIDS patients. Innate phagocytes in the lungs, such as dendritic cells (DCs) and macrophages, are the first cells to interact with the pathogen. Neutrophils, another innate phagocyte, are recruited to the lungs during cryptococcal infection. These innate cells are involved in early detection of C. neoformans, as well as the removal and clearance of cryptococcal infections. However, C. neoformans has developed ways to interfere with these processes, allowing for the evasion of the host’s innate immune system. Additionally, the innate immune cells have the ability to aid in cryptococcal pathogenesis. This review discusses recent literature on the interactions of innate pulmonary phagocytes with C. neoformans.
登录
查看更多内容
影响因子:
4.6
作者:
Bryan AM;Del Poeta M;Luberto C
通讯作者:
Luberto C
DOI:
10.4049/jimmunol.0901316
发表时间:
2009-08-01
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
Szymczak WA;Deepe GS Jr
通讯作者:
Deepe GS Jr
DOI:
10.3390/jof4010033
发表时间:
2018-03-07
期刊:
Journal of fungi (Basel, Switzerland)
影响因子:
--
作者:
Campuzano A;Wormley FL
通讯作者:
Wormley FL
影响因子:
6.7
作者:
Islam A;Li SS;Oykhman P;Timm-McCann M;Huston SM;Stack D;Xiang RF;Kelly MM;Mody CH
通讯作者:
Mody CH
影响因子:
2.9
作者:
Chiller, T;Farrokhshad, K;Stevens, DA
通讯作者:
Stevens, DA