Organophosphorous pesticide exposures and sperm quality.
Organophosphorous pesticide exposures and sperm quality.
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DOI：
10.1016/j.reprotox.2010.08.006
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发表时间：
2011-01
期刊：
影响因子：
--
通讯作者：
Xu X
中科院分区：
文献类型：
--
作者：
Perry MJ;Venners SA;Chen X;Liu X;Tang G;Xing H;Barr DB;Xu X
许多美国人暴露于低水平的有机磷（OP）农药。目前还不清楚这些暴露是否会影响精子的产生。我们调查了来自中国东部中华人民共和国农村地区的新婚男性尿OP杀虫剂代谢产物与精子浓度和活力之间是否存在关联。根据调整相关协变量后的精子浓度和活力的中位残差值，纳入94例病例和95例对照。他们的尿液中分析了六种二烷基磷酸盐（DAP）化合物。在调整人口统计学和暴露变量后，与尿中磷酸二甲酯浓度较低的男性相比，尿中磷酸二甲酯浓度较高的男性成为病例的几率更大（比值比=1.30，95%置信区间1.02-1.65）。其他DAP浓度在病例组和对照组之间无显著差异。应在环境暴露研究中进一步探讨精子暴露与精子浓度和活力的关系。
Many Americans are exposed to low levels of organophosphorous (OP) pesticides. In is unclear whether these exposures impact sperm production. We investigated whether there was an association between urinary OP insecticide metabolites and sperm concentration and motility in newly married men from a rural area of eastern People’s Republic of China. Ninety-four cases and 95 controls were included based on their median residual value of sperm concentration and motility after adjusting for relevant covariates. Their urine was analyzed for six dialkylphosphate (DAP) compounds. After adjustment for demographic and exposure variables, the odds of being a case were greater (Odds Ratio=1.30, 95% Confidence Interval 1.02-1.65) in men with higher urinary concentrations of dimethylphosphate (DMP) compared to men with lower levels. No significant differences between cases and controls were found among the other DAP concentrations. DMP exposure and sperm concentration and motility should be explored further in environmental exposure studies.
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影响因子：
10.4
作者：
Eskenazi B;Harley K;Bradman A;Weltzien E;Jewell NP;Barr DB;Furlong CE;Holland NT
通讯作者：
Holland NT
DOI：
10.1097/00043764-200010000-00004
发表时间：
2000-10-01
影响因子：
3.2
作者：
Padungtod, C;Savitz, DA;Xu, XP
通讯作者：
Xu, XP
影响因子：
3.8
作者：
Sánchez-Peña, LC;Reyes, BE;Quintanilla-Vega, B
通讯作者：
Quintanilla-Vega, B
DOI：
10.1038/sj.jea.7500322
发表时间：
2004-05-01
期刊：
JOURNAL OF EXPOSURE ANALYSIS AND ENVIRONMENTAL EPIDEMIOLOGY
影响因子：
--
作者：
Bravo, R;Caltabiano, LM;Barr, DB
通讯作者：
Barr, DB
DOI：
10.1179/oeh.2006.12.4.355
发表时间：
2006-10-01
影响因子：
--
作者：
Yucra, Sandra;Rubio, Julio;Gonzales, Gustavo F.
通讯作者：
Gonzales, Gustavo F.