What the reproductive number R(0) can and cannot tell us about COVID-19 dynamics.
What the reproductive number R(0) can and cannot tell us about COVID-19 dynamics.
复制标题
DOI:
10.1016/j.tpb.2020.12.003
复制
发表时间:
2021-03
影响因子:
1.4
通讯作者:
Kennedy DA
中科院分区:
文献类型:
--
作者:
Shaw CL;Kennedy DA
The reproductive number (or , the initial reproductive number in an immune-naïve population) has long been successfully used to predict the likelihood of pathogen invasion, to gauge the potential severity of an epidemic, and to set policy around interventions. However, often ignored complexities have generated confusion around use of the metric. This is particularly apparent with the emergent pandemic virus SARS-CoV-2, the causative agent of COVID-19. We address some misconceptions about the predictive ability of the reproductive number, focusing on how it changes over time, varies over space, and relates to epidemic size by referencing the mathematical definition of and examples from the current pandemic. We hope that a better appreciation of the uses, nuances, and limitations of and facilitates a better understanding of epidemic spread, epidemic severity, and the effects of interventions in the context of SARS-CoV-2.
登录
查看更多内容
影响因子:
9.8
作者:
Althouse BM;Wenger EA;Miller JC;Scarpino SV;Allard A;Hébert-Dufresne L;Hu H
通讯作者:
Hu H
影响因子:
11.7
作者:
Chowell G;Sattenspiel L;Bansal S;Viboud C
通讯作者:
Viboud C
影响因子:
11.8
作者:
Delamater, Paul L.;Street, Erica J.;Jacobsen, Kathryn H.
通讯作者:
Jacobsen, Kathryn H.
影响因子:
6.1
作者:
de Roos, AM;Leonardsson, K;Mittelbach, GG
通讯作者:
Mittelbach, GG
影响因子:
56.9
作者:
Britton, Tom;Ball, Frank;Trapman, Pieter
通讯作者:
Trapman, Pieter