Erythema Multiforme and COVID-19: What Do We Know?
Erythema Multiforme and COVID-19: What Do We Know?
复制标题
DOI：
10.3390/medicina57080828
复制
发表时间：
2021-08-16
期刊：
影响因子：
--
通讯作者：
Patruno C
中科院分区：
文献类型：
--
作者：
Bennardo L;Nisticò SP;Dastoli S;Provenzano E;Napolitano M;Silvestri M;Passante M;Patruno C
背景：多形红斑（EM）是一种急性皮疹，通常与感染有关，很少与药物有关。该综述旨在评估多形性红斑与2019冠状病毒病（COVID-19）之间的关联。方法：系统检索PubMed/MEDLINE、Scimago Scopus和ISI/Web of Science。对原始文献、病例系列或病例报告进行评价和选择。结果：共纳入14篇文献，共描述70例患者。EM是一种在COVID-19中很少发生的皮疹，在大多数情况下，与对病毒的超敏反应有关。在这些情况下，EM似乎影响30岁以下或55岁以上的患者。偶尔，用于COVID-19管理的一些药物可能会诱发EM，尤其是羟氯喹。这三组患者似乎有不同的临床特征和病程。结论：根据这些数据，可以初步提出与COVID-19相关的EM或EM样出疹可能分为三种类型：病毒相关的青少年型（影响<30岁的患者），病毒相关的老年型（影响>55岁的患者）和药物诱导型。皮疹的发生似乎与COVID-19的严重程度和临床病程无关。
Background: Erythema multiforme (EM) is an acute cutaneous eruption often associated with infections and more rarely with drugs. This review aimed to evaluate the association between erythema multiforme and coronavirus disease 2019 (COVID-19). Methods: A systematic search of PubMed/MEDLINE, Scimago Scopus, and ISI/Web of Science was performed. Original articles, case series, or case reports were evaluated and selected. Results: Fourteen articles were selected, describing a total of 70 patients. EM is a cutaneous eruption rarely occurring in COVID-19 and is, in most cases, associated with a hypersensitivity reaction to the virus. In these cases, EM seems to affect patients younger than 30 years or older than 55 years. Infrequently, some drugs used in the management of COVID-19 may induce EM, especially hydroxychloroquine. The three groups of patients seem to have different clinical characteristics and courses. Conclusions: From these data, it is possible to preliminarily propose that EM or EM-like eruptions linked to COVID-19 might be divided into three types: the virus-related juvenile type (affecting patients <30-year-old), the virus-related older type (affecting patients >55 years), and the drug-induced type. The occurrence of a skin rash does not seem to be related to the severity and clinical course of COVID-19.
登录
查看更多内容
DOI：
10.1016/j.amsu.2021.102591
发表时间：
2021-08
期刊：
Annals of medicine and surgery (2012)
影响因子：
--
作者：
Bouabdella S;Benkaraache M;Almheirat Y;Zizi N;Dikhaye S
通讯作者：
Dikhaye S
影响因子：
1.5
作者：
Torrelo, Antonio;Andina, David;Colmenero, Isabel
通讯作者：
Colmenero, Isabel
影响因子：
3.6
作者：
Schwartz, Robert A.;Janniger, Camila K.
通讯作者：
Janniger, Camila K.
第二剂 mRNA-1273 (Moderna) COVID-19 疫苗后出现大疱性药疹：病例报告。
影响因子：
6.7
作者：
Kong J;Cuevas-Castillo F;Nassar M;Lei CM;Idrees Z;Fix WC;Halverstam C;Mir A;Elbendary A;Mathew A
通讯作者：
Mathew A
影响因子：
3.6
作者：
Catala, Alba;Galvan-Casas, Cristina;Garcia-Doval, Ignacio
通讯作者：
Garcia-Doval, Ignacio