Internal and External Validity of Social Media and Mobile Technology-Driven HPV Vaccination Interventions: Systematic Review Using the Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM) Framework.
Internal and External Validity of Social Media and Mobile Technology-Driven HPV Vaccination Interventions: Systematic Review Using the Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM) Framework.
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DOI：
10.3390/vaccines9030197
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发表时间：
2021-02-26
期刊：
影响因子：
7.8
通讯作者：
Montealegre JR
中科院分区：
文献类型：
--
作者：
Asare M;Popelsky B;Akowuah E;Lanning BA;Montealegre JR
社交媒体人乳头瘤病毒（HPV）疫苗接种干预措施显示出提高HPV疫苗接种率的希望。将有效的干预措施落实到现实世界实践中的一个重要考虑因素是干预措施的转化潜力或外部有效性。为此，我们进行了系统的文献综述，以描述目前关于社交媒体HPV疫苗接种相关干预措施的外部有效性的证据。与外部效度相关的结构是基于可及性、有效性、采纳、实施、维护（RE-AIM）框架。2006年至2020年间发表的17篇文章符合纳入标准。三名研究人员使用经过验证的RE-AIM框架独立编码每篇文章。与第四位评审员讨论了不一致的代码，以达成共识。在这17项研究中，3项是初步疗效研究，10项是评价疗效的随机对照试验（RCT），1项是基于人群的研究，3项未明确说明进行了哪种类型的研究。反映了研究类型的这种分布，在所有研究中，报告RE-AIM维度的平均水平各不相同，达到记录90.8%，有效性（72.1%），采用（40.3%），实施（45.6%）和维护（26.5%）。这篇综述表明，虽然目前HPV疫苗接种社交媒体驱动的干预措施提供了足够的内部有效性（覆盖范围和有效性）信息，但很少有人旨在收集将干预措施转化为真实的世界实施所需的外部有效性数据。我们的数据表明，需要进行实施研究，以将HPV疫苗接种相关干预措施付诸实践。本次审查包括加强这些HPV疫苗接种社交媒体相关干预措施的设计和报告的建议。
Social media human papillomavirus (HPV) vaccination interventions show promise for increasing HPV vaccination rates. An important consideration for the implementation of effective interventions into real-world practice is the translation potential, or external validity, of the intervention. To this end, we conducted a systematic literature review to describe the current body of evidence regarding the external validity of social media HPV vaccination-related interventions. Constructs related to external validity were based on the reach, effectiveness, adoption, implementation, maintenance (RE-AIM) framework. Seventeen articles published between 2006 and 2020 met the inclusion criteria. Three researchers independently coded each article using a validated RE-AIM framework. Discrepant codes were discussed with a fourth reviewer to gain consensus. Of these 17 studies, 3 were pilot efficacy studies, 10 were randomized controlled trials (RCTs) to evaluate effectiveness, 1 was a population-based study, and 3 did not explicitly state which type of study was conducted. Reflecting this distribution of study types, across all studies the mean level of reporting RE-AIM dimensions varied with reach recording 90.8%, effectiveness (72.1%), adoption (40.3%), implementation (45.6%), and maintenance (26.5%). This review suggests that while the current HPV vaccination social media-driven interventions provide sufficient information on internal validity (reach and effectiveness), few have aimed to gather data on external validity needed to translate the interventions into real world implementation. Our data suggest that implementation research is needed to move HPV vaccination-related interventions into practice. Included in this review are recommendations for enhancing the design and reporting of these HPV vaccination social media-related interventions.
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