Cognition, academic achievement, language, and psychopathology in pediatric chronic epilepsy: Short-term outcomes.
Cognition, academic achievement, language, and psychopathology in pediatric chronic epilepsy: Short-term outcomes.
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DOI：
10.1016/j.yebeh.2010.03.015
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发表时间：
2010-07
期刊：
影响因子：
--
通讯作者：
Caplan R
中科院分区：
文献类型：
--
作者：
Jones JE;Siddarth P;Gurbani S;Shields WD;Caplan R
癫痫儿童和对照组儿童被随访两年以上。癫痫的合并症，通常定义为与智商，学业成绩，语言和精神病理学相关的问题，进行了前瞻性评估。假设随着时间的推移，a）合并症的存在将预测更差的结局，B）癫痫变量将对合并症产生负面影响。该研究包括39名复杂部分性癫痫发作（CPS）儿童，25名儿童失神癫痫（CAE）和27名健康儿童，年龄为7.6-16.1岁。在所有三个组中，这些结果在间隔期间的稳定性方面值得注意。此外，基线癫痫发作变量和变化的时间间隔似乎发挥作用的智商和数学成绩的癫痫儿童与平均智商和阅读成绩分数低于平均智商。然而，基线和随访时的癫痫发作变量不是DSM-IV诊断、抑郁、焦虑或行为问题的预测因子。
Children with epilepsy and control children were followed over a two year interval. Comorbidities of epilepsy, often defined as problems related to IQ, academic achievement, language, and psychopathology, were evaluated prospectively. It was hypothesized that over time a) the presence of comorbidities would predict worse outcomes, and b) epilepsy variables would negatively impact comorbidities. The study included 39 children with complex partial seizures (CPS), 25 children childhood absence epilepsy (CAE), and 27 healthy children, aged 7.6-16.1 years. The findings were notable for stability over the interval in all three groups. Additionally, baseline seizure variables and change over the interval appear to play a role in IQ and math achievement scores of children with epilepsy with average IQ and in the reading achievement scores of those with below average IQ. However, seizures variables at baseline and follow-up were not predictors of DSM-IV diagnoses, depression, anxiety or behavioral problems.
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