Neural correlates of ongoing conscious experience: both task-unrelatedness and stimulus-independence are related to default network activity.
Neural correlates of ongoing conscious experience: both task-unrelatedness and stimulus-independence are related to default network activity.
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持续有意识体验的神经相关性：任务无关性和刺激无关性都与默认网络活动有关。
DOI：
10.1371/journal.pone.0016997
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发表时间：
2011-02-14
期刊：
影响因子：
3.7
通讯作者：
D'Argembeau A
中科院分区：
文献类型：
--
作者：
Stawarczyk D;Majerus S;Maquet P;D'Argembeau A
默认模式网络（DMN）是一组大脑区域，与需要持续专注于外部刺激的任务相比，这些区域在休息时始终显示出更高的活动。DMN背后的认知过程仍然是一个有争议的问题。也有人提出，DMN活动反映了对外部刺激或内部产生的想法的注意力不集中。本研究旨在通过调查任务执行过程中可能发生的各种意识体验的神经相关性来澄清这一问题。四类意识体验（即，完全专注于任务，由无关的感觉/感知引起的分心，与任务评估相关的干扰思想，以及走神），沿着沿着两个维度（“任务相关性”和“刺激依赖性”）变化，当参与者执行进行/不进行任务时，使用思想探针进行采样。根据报告的主观经验，对每个探头之前的间隔进行分析，结果显示，这两个维度都与解释DMN几个区域的活动有关，即内侧前额叶皮质、后扣带皮质/楔前叶和后下顶叶。值得注意的是，两个维度的加性效应被证明为中线DMN区域。另一方面，侧颞区（也是DMN的一部分）与刺激无关的报告具体相关。这些结果表明，中线DMN区域是内部思维和外部非集中注意力期间活跃的认知过程的基础。他们还加强了这样一种观点，即DMN可以细分为不同的子组件，并揭示了在研究DMN可能的功能作用时，考虑刺激依赖和任务相关维度的意识体验的必要性。
The default mode network (DMN) is a set of brain regions that consistently shows higher activity at rest compared to tasks requiring sustained focused attention toward externally presented stimuli. The cognitive processes that the DMN possibly underlies remain a matter of debate. It has alternately been proposed that DMN activity reflects unfocused attention toward external stimuli or the occurrence of internally generated thoughts. The present study aimed at clarifying this issue by investigating the neural correlates of the various kinds of conscious experiences that can occur during task performance. Four classes of conscious experiences (i.e., being fully focused on the task, distractions by irrelevant sensations/perceptions, interfering thoughts related to the appraisal of the task, and mind-wandering) that varied along two dimensions (“task-relatedness” and “stimulus-dependency”) were sampled using thought-probes while the participants performed a go/no-go task. Analyses performed on the intervals preceding each probe according to the reported subjective experience revealed that both dimensions are relevant to explain activity in several regions of the DMN, namely the medial prefrontal cortex, posterior cingulate cortex/precuneus, and posterior inferior parietal lobe. Notably, an additive effect of the two dimensions was demonstrated for midline DMN regions. On the other hand, lateral temporal regions (also part of the DMN) were specifically related to stimulus-independent reports. These results suggest that midline DMN regions underlie cognitive processes that are active during both internal thoughts and external unfocused attention. They also strengthen the view that the DMN can be fractionated into different subcomponents and reveal the necessity to consider both the stimulus-dependent and the task-related dimensions of conscious experiences when studying the possible functional roles of the DMN.
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DOI：
10.1037/1076-898x.14.1.73
发表时间：
2008-03
期刊：
Journal of experimental psychology. Applied
影响因子：
--
作者：
Forster S;Lavie N
通讯作者：
Lavie N
DOI：
10.1073/pnas.0504136102
发表时间：
2005-07-05
影响因子：
11.1
作者：
Fox, MD;Snyder, AZ;Raichle, ME
通讯作者：
Raichle, ME
影响因子：
1.7
作者：
Dumontheil, Iroise;Gilbert, Sam J.;Burgess, Paul W.
通讯作者：
Burgess, Paul W.
影响因子：
5.7
作者：
D'Argembeau, A;Collette, F;Salmon, E
通讯作者：
Salmon, E
影响因子：
2.5
作者：
Andrews-Hanna, Jessica R.;Reidler, Jay S.;Buckner, Randy L.
通讯作者：
Buckner, Randy L.