The Big Breakfast Study: Chrono-nutrition influence on energy expenditure and bodyweight.
The Big Breakfast Study: Chrono-nutrition influence on energy expenditure and bodyweight.
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DOI：
10.1111/nbu.12323
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发表时间：
2018-06
影响因子：
3.3
通讯作者：
Johnstone AM
中科院分区：
文献类型：
--
作者：
Ruddick-Collins LC;Johnston JD;Morgan PJ;Johnstone AM
越来越多的证据强调了生物钟作为能量平衡和新陈代谢调节器的重要性。最近对人类的研究表明，摄入的卡路里在早上比在晚上更有效地利用，这是通过改善体重减轻表现出来的，即使在等能量的卡路里摄入量下。这种增强的早晨能量代谢背后的机制尚不清楚，尽管它可能是由于行为适应或生理和能量代谢的昼夜节律驱动的变化。因此，新资助的大早餐研究的一个主要目标是通过探索能量消耗的行为和生理适应以及潜在的昼夜节律生物学来研究这种放大的早晨产热导致增强减肥的机制基础。本报告简要讨论了目前的研究联系进餐时间，昼夜节律和代谢;突出了研究差距;并提供了正在进行的研究的概述，作为医学研究理事会资助的大早餐研究的一部分。
A growing body of evidence highlights the importance of the biological clock as a modulator of energy balance and metabolism. Recent studies in humans have shown that ingested calories are apparently utilised more efficiently in the morning than in the evening and this is manifest through improved weight loss, even under iso‐energetic calorie intake. The mechanisms behind this enhanced morning energy metabolism are not yet clear, although it may result from behavioural adaptations or circadian driven variations in physiology and energy metabolism. A major objective of the newly funded Big Breakfast Study therefore is to investigate the mechanistic basis of this amplified morning thermogenesis leading to enhanced weight loss, by exploring behavioural and physiological adaptations in energy expenditure alongside the underlying circadian biology. This report briefly discusses the current research linking meal timing, circadian rhythms and metabolism; highlights the research gaps; and provides an overview of the studies being undertaken as part of the Medical Research Council‐funded Big Breakfast Study.
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影响因子：
5
作者：
Ma, YS;Bertone, ER;Ockene, IS
通讯作者：
Ockene, IS
影响因子：
7.1
作者：
McHill, Andrew W.;Phillips, Andrew J. K.;Klerman, Elizabeth B.
通讯作者：
Klerman, Elizabeth B.
影响因子：
4.8
作者：
Froy, O;Chapnik, N;Miskin, R
通讯作者：
Miskin, R
DOI：
10.1002/oby.21189
发表时间：
2015-10
期刊：
Obesity (Silver Spring, Md.)
影响因子：
--
作者：
Morris CJ;Garcia JI;Myers S;Yang JN;Trienekens N;Scheer FA
通讯作者：
Scheer FA
DOI：
10.3945/ajcn.114.083402
发表时间：
2014-08
期刊：
The American journal of clinical nutrition
影响因子：
--
作者：
Betts JA;Richardson JD;Chowdhury EA;Holman GD;Tsintzas K;Thompson D
通讯作者：
Thompson D