Evening chronotype is associated with changes in eating behavior, more sleep apnea, and increased stress hormones in short sleeping obese individuals.
Evening chronotype is associated with changes in eating behavior, more sleep apnea, and increased stress hormones in short sleeping obese individuals.
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DOI：
10.1371/journal.pone.0056519
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发表时间：
2013
期刊：
影响因子：
3.7
通讯作者：
Sleep Extension Study Group
中科院分区：
文献类型：
--
作者：
Lucassen EA;Zhao X;Rother KI;Mattingly MS;Courville AB;de Jonge L;Csako G;Cizza G;Sleep Extension Study Group
睡眠时间短和睡眠质量下降是肥胖及其相关疾病的新风险因素。时间类型是一种反映个人在睡眠时间和其他行为方面偏好的属性，是从早晨到晚上的连续体。生理时钟型与肥胖的关系的重要性大多是未知的。晚上类型倾向于有不健康的饮食习惯，并且比早上类型更频繁地遭受心理问题，因此我们假设晚上可能会影响一组报告每晚睡眠少于6.5小时的肥胖个体的健康参数。分析了来自睡眠延长研究的肥胖（BMI：38.5±6.4 kg/m2）和睡眠时间短（体动记录为5.8±0.8 h/夜）参与者（n =119）的基线数据（ www.ClinicalTrials.gov，标识符NCT 00261898）。 评估包括Horne和Ostberg晨间-夜间问卷、3天饮食摄入日记、14天睡眠日记、14天活动记录仪和睡眠呼吸暂停测量。测定24小时尿游离皮质醇、24小时尿去甲肾上腺素和肾上腺素水平、早晨血浆ACTH和血清皮质醇、空腹血糖和胰岛素以及血脂参数。无论是工作日还是非工作日，晚上都与当天晚些时候吃饭有关。向晚上的进展与BMI、静息心率、食物份量的增加以及进食次数和HDL-胆固醇的减少有关。夜间型的24 h尿肾上腺素和早晨血浆ACTH水平明显高于早晨型，早晨静息心率高于早晨型。此外，夜间类型更容易发生睡眠呼吸暂停，与BMI或颈围无关。晚上进食时间较晚，倾向于少食多餐，HDL胆固醇水平较低。此外，晚上型的人有更多的睡眠呼吸暂停和更高的压力激素。因此，肥胖、长期睡眠不足的个体的夜间活动增加了与肥胖相关的心血管风险。
Short sleep duration and decreased sleep quality are emerging risk factors for obesity and its associated morbidities. Chronotype, an attribute that reflects individual preferences in the timing of sleep and other behaviors, is a continuum from morningness to eveningness. The importance of chronotype in relation to obesity is mostly unknown. Evening types tend to have unhealthy eating habits and suffer from psychological problems more frequently than Morning types, thus we hypothesized that eveningness may affect health parameters in a cohort of obese individuals reporting sleeping less than 6.5 hours per night. Baseline data from obese (BMI: 38.5±6.4 kg/m2) and short sleeping (5.8±0.8 h/night by actigraphy) participants (n = 119) of the Sleep Extension Study were analyzed (www.ClinicalTrials.gov, identifier NCT00261898). Assessments included the Horne and Ostberg Morningness-Eveningness questionnaire, a three-day dietary intake diary, a 14-day sleep diary, 14 days of actigraphy, and measurements of sleep apnea. Twenty-four hour urinary free cortisol, 24 h urinary norepinephrine and epinephrine levels, morning plasma ACTH and serum cortisol, fasting glucose and insulin, and lipid parameters were determined. Eveningness was associated with eating later in the day on both working and non-working days. Progression towards eveningness was associated with an increase in BMI, resting heart rate, food portion size, and a decrease in the number of eating occasions and HDL-cholesterol. Evening types had overtly higher 24 h urinary epinephrine and morning plasma ACTH levels, and higher morning resting heart rate than Morning types. In addition, Evening types more often had sleep apnea, independent of BMI or neck circumference. Eveningness was associated with eating later and a tendency towards fewer and larger meals and lower HDL-cholesterol levels. In addition, Evening types had more sleep apnea and higher stress hormones. Thus, eveningness in obese, chronically sleep-deprived individuals compounds the cardiovascular risk associated with obesity.
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影响因子：
4.2
作者：
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通讯作者：
de Castro, JM
影响因子：
4.2
作者：
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影响因子：
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作者：
BUYSSE, DJ;REYNOLDS, CF;KUPFER, DJ
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Allison DB
影响因子：
5.4
作者：
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de Jonge L