Interactions between parental traits, environmental harshness and growth rate in determining telomere length in wild juvenile salmon
Interactions between parental traits, environmental harshness and growth rate in determining telomere length in wild juvenile salmon
复制标题
亲代性状、环境恶劣程度和生长速率之间的相互作用在确定野生幼鲑鱼端粒长度方面的作用
作者：
Darryl McLennan;John D. Armstrong;D. C. Stewart;S. Mckelvey;W. Boner;Pat Monaghan;Neil B. Metcalfe
更大的体型带来了许多好处，例如增加繁殖成功率，逃避捕食者的能力以及提高竞争能力和社会地位。然而，个人很少最大限度地提高他们的增长率，这表明这是有代价的。其中一个代价可能是端粒的更快磨损，端粒覆盖真核生物染色体的末端，在染色体保护中起着重要作用。相对短的端粒长度指示较差的生物学状态，包括较差的组织和器官性能、降低的潜在寿命和增加的疾病易感性。生长过程中端粒的丢失也可能被环境因素加速，但这些因素很少在自然环境中进行实验操作。使用野生系统，涉及实验操作的少年大西洋鲑鱼萨尔莫salar在苏格兰流，我们发现，在幼鱼端粒长度的影响父母的性状和直接的环境影响。我们发现，生长较快的鱼类具有较短的端粒，如果生长发生在更恶劣的环境中，则成本更高（就端粒长度减少而言）。我们还发现，后代端粒长度与其父亲（而不是母亲）的生长历史之间存在正相关，以父亲在海上度过的年数为代表。这表明生长条件和父母生活史可能对个体寿命产生长期影响。
A larger body size confers many benefits, such as increased reproductive success, ability to evade predators and increased competitive ability and social status. However, individuals rarely maximize their growth rates, suggesting that this carries costs. One such cost could be faster attrition of the telomeres that cap the ends of eukaryotic chromosomes and play an important role in chromosome protection. A relatively short telomere length is indicative of poor biological state, including poorer tissue and organ performance, reduced potential longevity and increased disease susceptibility. Telomere loss during growth may also be accelerated by environmental factors, but these have rarely been subjected to experimental manipulation in the natural environment. Using a wild system involving experimental manipulations of juvenile Atlantic salmon Salmo salar in Scottish streams, we found that telomere length in juvenile fish was influenced by parental traits and by direct environmental effects. We found that faster‐growing fish had shorter telomeres and there was a greater cost (in terms of reduced telomere length) if the growth occurred in a harsher environment. We also found a positive association between offspring telomere length and the growth history of their fathers (but not mothers), represented by the number of years fathers had spent at sea. This suggests that there may be long‐term consequences of growth conditions and parental life history for individual longevity.
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影响因子：
11.1
作者：
V. Zakian
通讯作者：
V. Zakian
影响因子：
14.9
作者：
Cawthon, RM
通讯作者：
Cawthon, RM
DOI：
10.1073/pnas.89.21.10114
发表时间：
1992-11-01
影响因子：
11.1
作者：
ALLSOPP, RC;VAZIRI, H;HARLEY, CB
通讯作者：
HARLEY, CB
DOI：
10.1002/j.1460-2075.1994.tb06620.x
发表时间：
1994-07
期刊：
The EMBO Journal
影响因子：
--
作者：
L. L. Mantell-L.;C. Greider
通讯作者：
L. L. Mantell-L.;C. Greider
捕食者对幼年大西洋鲑鱼（Salmo salar）能量影响的季节性变化。
DOI：
10.1139/f2011-123
发表时间：
2011
期刊：
Canadian journal of fisheries and aquatic sciences. Journal canadien des sciences halieutiques et aquatiques
影响因子：
--
作者：
Ward,DarrenM;Nislow,KeithH;Folt,CarolL
通讯作者：
Folt,CarolL