The effect of eating sea cucumber jelly on Candida load in the oral cavity of elderly individuals in a nursing home.
The effect of eating sea cucumber jelly on Candida load in the oral cavity of elderly individuals in a nursing home.
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DOI：
10.3390/md11124993
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发表时间：
2013-12-11
期刊：
影响因子：
5.4
通讯作者：
Kishi M
中科院分区：
文献类型：
--
作者：
Yano A;Abe A;Aizawa F;Yamada H;Minami K;Matsui M;Kishi M
我们对一家养老院的老年人进行了一项双盲随机对照研究，以调查食用含海参果冻对他们口腔念珠菌负荷的影响。果冻中含有刺参的一种水解物，其中含有被称为全毒素的三萜糖苷。全毒素具有杀菌作用，对白色念珠菌的最低抑菌浓度为7微克/毫升。养老院的8个人服用了海参果冻一周，并在干预前后对他们的口腔念珠菌进行了计数。9个人服用了没有日本血吸虫的对照果冻。海参果冻对口腔念珠菌有抑制作用。因此，日常食用日本血吸虫果冻有可能减少养老院老年人的口腔念珠菌负荷。
We conducted a double-blind randomized controlled study of elderly individuals in a nursing home to investigate the effect of the consumption of jelly containing sea cucumber on their oral Candida load. The jelly contained a hydrolysate of the sea cucumber Stichopus japonicus, which contained triterpene glycosides called holotoxins. The holotoxins worked as a fungicide, and their minimum inhibitory concentrations for Candida albicans were 7 µg/mL. Eight individuals in the nursing home took the sea cucumber jelly for a week and their oral Candida were counted before and after the intervention. Nine individuals took a control jelly without S. japonicus. The sea cucumber jelly showed inhibitory effects on the oral Candida. Thus, daily consumption of the S. japonicus jelly has the potential to reduce the oral Candida load in the elderly in nursing homes.
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影响因子：
5.4
作者：
Bordbar S;Anwar F;Saari N
通讯作者：
Saari N
影响因子：
2.8
作者：
Van Dyck, Severine;Caulier, Guillaume;Flammang, Patrick
通讯作者：
Flammang, Patrick
影响因子：
4.9
作者：
Bergsson, G;Arnfinnsson, J;Thormar, H
通讯作者：
Thormar, H
影响因子：
--
作者：
Dongari-Bagtzoglou, A.;Dwivedi, P.;Burleson, J.
通讯作者：
Burleson, J.
DOI：
10.1067/moe.2002.126024
发表时间：
2002-11-01
期刊：
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY
影响因子：
--
作者：
Maza, JL;Elguezabal, N;Pontón, J
通讯作者：
Pontón, J