Urban landscapes increase dispersal, gene flow, and pathogen transmission potential in banded mongoose (Mungos mungo) in northern Botswana.
Urban landscapes increase dispersal, gene flow, and pathogen transmission potential in banded mongoose (Mungos mungo) in northern Botswana.
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城市景观增加扩散，基因流，和病原体传播的潜力在带状猫鼬（蒙戈蒙戈）在北方博茨瓦纳。
DOI：
10.1002/ece3.7487
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发表时间：
2021-07
影响因子：
2.6
通讯作者：
Alexander KA
中科院分区：
文献类型：
--
作者：
Verble K;Hallerman EM;Alexander KA
同种生物在景观上的联系方式以及土地利用对这些动态的影响，可对疾病传播产生强烈影响。在博茨瓦纳北部，领地和群居的带状猫鼬（Mungos mungo）生活在城市和自然景观中，感染了一种新型结核分枝杆菌复合病原体，mungi。利用从带状猫鼬粪便和组织样本（n = 168）中提取的DNA扩增的微卫星标记，我们评估了12个种群的遗传结构、个体扩散和基因流动。遗传结构是可检测的，并且在组间具有中等强度（F ST = 0.086）， K = 7是最佳支持的遗传簇数。某些部队中混合的迹象表明，通过最近的融合事件形成了新的群体。居住在自然区域的部队分化程度（F ST = 0.102）高于城市景观中的部队分化程度（F ST = 0.081）。虽然这表明城市居民群体之间的基因流动水平有所提高，但从自然土地类型中纳入较少数量的研究群体可能影响了这些发现。在确认感染蒙氏分枝杆菌的个体中，大多数（73%,n = 11）被分配到其出生组，这与先前将较低传播水平与感染联系起来的观察结果一致。确定了21个可能的分散个体，所有疑似移徙者都来自城市景观内的部队。研究结果表明，城市化景观可能会增加基因流动和传播行为，同时增加病原体传播的风险。随着城市景观的扩大，越来越需要了解土地利用和病原体感染如何改变野生动物的行为和疾病传播潜力。利用从带状猫鼬粪便和组织样本（n = 168）中扩增的DNA微卫星标记，我们评估了博茨瓦纳北部带状猫鼬（Mungos mungo）的基因流动。这一物种生活在城市和自然景观中，感染了一种新的结核分枝杆菌复合病原体，芒氏分枝杆菌。我们的研究结果表明，城市景观可能会增加猫鼬群体之间的运动，基因流动和潜在的病原体传播，潜在地突出了城市景观可能对野生动物行为和生态的重要影响。
Disease transmission can be strongly influenced by the manner in which conspecifics are connected across a landscape and the effects of land use upon these dynamics. In northern Botswana, the territorial and group‐living banded mongoose (Mungos mungo) lives across urban and natural landscapes and is infected with a novel Mycobacterium tuberculosis complex pathogen, M. mungi. Using microsatellite markers amplified from DNA derived from banded mongoose fecal and tissue samples (n = 168), we evaluated population genetic structure, individual dispersal, and gene flow for 12 troops. Genetic structure was detectable and moderately strong across groups (F ST = 0.086), with K = 7 being the best‐supported number of genetic clusters. Indications of admixture in certain troops suggest formation of new groups through recent fusion events. Differentiation was higher for troops inhabiting natural areas (F ST = 0.102) than for troops in urban landscapes (F ST = 0.081). While this suggests increased levels of gene flow between urban‐dwelling troops, the inclusion of a smaller number of study troops from natural land types may have influenced these findings. Of those individuals confirmed infected with M. mungi, the majority (73%, n = 11) were assigned to their natal group which is consistent with previous observations linking lower levels of dispersal with infection. Twenty‐one probable dispersing individuals were identified, with all suspected migrants originating from troops within the urban landscape. Findings suggest that urbanized landscapes may increase gene flow and dispersal behavior with a concomitant increase in the risk of pathogen spread. As urban landscapes expand, there is an increasing need to understand how land use and pathogen infection may change wildlife behavior and disease transmission potential. Using microsatellite markers amplified from DNA derived from banded mongoose fecal and tissue samples (n = 168), we evaluate gene flow in banded mongoose (Mungos mungo) in northern Botswana. This species lives across urban and natural landscapes and is infected with a novel Mycobacterium tuberculosis complex pathogen, M. mungi. Our results suggest that urban landscapes may increase mongoose movements between groups, gene flow, and potentially pathogen transmission potentially highlighting the critical influence urban landscapes may have on wildlife behavior and ecology.
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DOI：
10.1007/978-3-319-92373-4_8
发表时间：
2018-01-01
期刊：
CONNECTIONS BETWEEN ECOLOGY AND INFECTIOUS DISEASE
影响因子：
--
作者：
Alexander, Kathleen A.;Carlson, Colin J.;Blackburn, Jason K.
通讯作者：
Blackburn, Jason K.
影响因子：
2.5
作者：
Fairbanks, Bonnie M.;Hawley, Dana M.;Alexander, Kathleen A.
通讯作者：
Alexander, Kathleen A.
影响因子：
7.7
作者：
Excoffier, Laurent;Lischer, Heidi E. L.
通讯作者：
Lischer, Heidi E. L.
影响因子：
4.1
作者：
Cote, Heloise;Garant, Dany;Pelletier, Fanie
通讯作者：
Pelletier, Fanie
影响因子：
2.6
作者：
Flint, Bonnie Fairbanks;Hawley, Dana M.;Alexander, Kathleen A.
通讯作者：
Alexander, Kathleen A.