Capillary blood flow imaging within human finger cuticle using optical microangiography.
Capillary blood flow imaging within human finger cuticle using optical microangiography.
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DOI:
10.1002/jbio.201300154
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发表时间:
2015-01
影响因子:
2.8
通讯作者:
Wang, Ruikang K.
中科院分区:
文献类型:
--
作者:
Baran, Utku;Shi, Lei;Wang, Ruikang K.
关键词:
We report non-invasive 3D imaging of capillary blood flow within human finger cuticle by the use of Doppler optical microangiography (DOMAG) and ultra-high sensitive optical microangiography (UHS-OMAG) techniques. Wide velocity range DOMAG method is applied to provide RBC axial velocity mapping in capillary loops with ranges of ±0.9 mm/s and ±0.3 mm/s. Additionally, UHS-OMAG technique is engineered to acquire high resolution image of capillary morphology. The presented results are promising to facilitate clinical trials of treatment and diagnosis of various diseases such as diabetes, Raynaud's phenomenon, and connective tissue diseases by quantifying cutaneous blood flow changes within human finger cuticle. Maximum projection image of the bidirectional RBC axial velocity mapping in the human finger cuticle capillaries.
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